ID Q2GHP8_EHRCR Unreviewed; 304 AA.
AC Q2GHP8;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Transporter {ECO:0000313|EMBL:ABD45307.1};
GN OrderedLocusNames=ECH_0212 {ECO:0000313|EMBL:ABD45307.1};
OS Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Ehrlichia.
OX NCBI_TaxID=205920 {ECO:0000313|EMBL:ABD45307.1, ECO:0000313|Proteomes:UP000008320};
RN [1] {ECO:0000313|EMBL:ABD45307.1, ECO:0000313|Proteomes:UP000008320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC CRL-10679 / Arkansas {ECO:0000313|Proteomes:UP000008320};
RX PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M.,
RA Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.,
RA Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J., Daugherty S.C.,
RA Davidsen T., Durkin A.S., Gwinn M., Haft D.H., Selengut J.D.,
RA Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R.,
RA Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.;
RT "Comparative genomics of emerging human ehrlichiosis agents.";
RL PLoS Genet. 2:208-222(2006).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69) family.
CC {ECO:0000256|ARBA:ARBA00010145}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000236; ABD45307.1; -; Genomic_DNA.
DR RefSeq; WP_011452462.1; NC_007799.1.
DR AlphaFoldDB; Q2GHP8; -.
DR STRING; 205920.ECH_0212; -.
DR KEGG; ech:ECH_0212; -.
DR eggNOG; COG0679; Bacteria.
DR HOGENOM; CLU_056175_4_2_5; -.
DR OrthoDB; 9810457at2; -.
DR Proteomes; UP000008320; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR36838; AUXIN EFFLUX CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR36838:SF1; SLR1864 PROTEIN; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 304 AA; 33670 MW; 55E0FCA2FAF660C4 CRC64;
MFFILLSKIL PLYITVLLGF IAGKFLKIDS PSIARLLFYI MGPTVIFSGI SQTNINSEVL
SLPFLTWLVC CIMSAVVYYT SSFIFRDSTR NILAFSSGSS SMGFFGLPVA LAMFDNHTVS
IYLFCYVGML MFENSFGFYI AAQGIYTPKK CIIKLITSPA AHAAVMALCV NYFKIPIPSF
VHDVASNIRG AYVSLGMMLL GIAVANIKTF SIDWKLISIT LIIKYVLWPV LVLGCIILDK
LTIQLYNNDI YRALILLAII PMSGTGIILA TMLNNNPDKT AIMLLVNTII GLFYVPIMIS
ILLY
//
