ID Q2HFN8_CHAGB Unreviewed; 426 AA.
AC Q2HFN8;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Golgi apparatus membrane protein TVP38 {ECO:0000256|ARBA:ARBA00013533};
DE AltName: Full=Golgi apparatus membrane protein tvp38 {ECO:0000256|ARBA:ARBA00020673};
GN ORFNames=CHGG_00966 {ECO:0000313|EMBL:EAQ92731.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ92731.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC spindle migration. {ECO:0000256|ARBA:ARBA00002978}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640}.
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DR EMBL; CH408029; EAQ92731.1; -; Genomic_DNA.
DR RefSeq; XP_001220187.1; XM_001220186.1.
DR AlphaFoldDB; Q2HFN8; -.
DR STRING; 306901.Q2HFN8; -.
DR GeneID; 4387282; -.
DR VEuPathDB; FungiDB:CHGG_00966; -.
DR eggNOG; KOG3140; Eukaryota.
DR HOGENOM; CLU_041954_0_0_1; -.
DR InParanoid; Q2HFN8; -.
DR OMA; YHDEFTD; -.
DR OrthoDB; 2385736at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR47549:SF1; GOLGI APPARATUS MEMBRANE PROTEIN TVP38; 1.
DR PANTHER; PTHR47549; GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 115..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 174..289
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 45206 MW; E4D78A3439FF501D CRC64;
MPPPQGDDVF HDASSNRATS PPTIITTRPS TDTPTELNTN NLPPPPWTPR PKTPGVRRLS
PGRPGTASTT HTTATTITTL TTTTKSFLTT TLTTLTYLYQ RYTHFYASLP LHYQILVSLS
GLLILTLTIL LLIYSHTILV ALGAAAQTWR ARPLGWLPLW LATVATGFPP LIGYSTCVTL
AGFVYGFPAG WPLAASATVV GSAGAFAASR GVLRGYVQRL VGADARFVAL GQVLRRDGLG
VLVMIRLCPL PYSLSNGFLA TVGSLGVGQF VLATLAATPK LLVHVFIGWQ LSQLAEPGDK
MSGASRAINY ISMAAFGLLG FSVGLFIYRR TMARAAELAR EAQLEAGEAL LDGHDEVEEG
ITGDDLESGR MVDPDELDAA ALMDDDDISL WDASGDGYHD SWDDEPAGNG FGSNGRGKGG
INGATK
//
