ID Q2I6K0_STERE Unreviewed; 317 AA.
AC Q2I6K0;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 2.
DT 13-SEP-2023, entry version 46.
DE RecName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00012526};
DE EC=2.7.7.60 {ECO:0000256|ARBA:ARBA00012526};
OS Stevia rebaudiana (Stevia) (Eupatorium rebaudianum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Eupatorieae; Stevia.
OX NCBI_TaxID=55670 {ECO:0000313|EMBL:ABB88837.2};
RN [1] {ECO:0000313|EMBL:ABB88837.2}
RP NUCLEOTIDE SEQUENCE.
RA Kumar H., Kumar S., Ahuja P.S.;
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-
CC phosphate: step 2/6. {ECO:0000256|ARBA:ARBA00004787}.
CC -!- SIMILARITY: Belongs to the IspD/TarI cytidylyltransferase family. IspD
CC subfamily. {ECO:0000256|ARBA:ARBA00009789}.
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DR EMBL; DQ269452; ABB88837.2; -; mRNA.
DR AlphaFoldDB; Q2I6K0; -.
DR UniPathway; UPA00056; UER00093.
DR GO; GO:0050518; F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:UniProtKB-UniPathway.
DR CDD; cd02516; CDP-ME_synthetase; 1.
DR HAMAP; MF_00108; IspD; 1.
DR InterPro; IPR001228; IspD.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR018294; ISPD_synthase_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR00453; ispD; 1.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01128; IspD; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS01295; ISPD; 1.
PE 2: Evidence at transcript level;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 317 AA; 34952 MW; 92EE59C2AFAC41F4 CRC64;
MTILQVMSPL NASPSQILLS KPQIPSNSVY LPAVDLYRHP RLSSCYSSSK SNFNLVRKHS
ICSGFTVTCS ANDSAKTTNE KPEYVREKSV SVVLLAGGQG KRMGASMPKQ YLPLLGQPIA
LYSFYTFSRM REVKEIVVVC DPSYQDIFED ARDNISVDLK FALPGKERQD SVFSGLQSID
LASELVCIHD SARPLVTSGD VLKVLNDGLR VGASVLGVPA KATIKEGNSE SFVVKTLDRK
TLWEMQTPQV IKPDLLKKGF ELVNREGLEV TDDVSIVEHL KHPVYITQGS YTNIKVTTPD
DLLLAERILN NDSFVPA
//
