ID Q2JKE0_SYNJB Unreviewed; 426 AA.
AC Q2JKE0;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Carboxylesterase, beta-lactamase family {ECO:0000313|EMBL:ABD02849.1};
GN OrderedLocusNames=CYB_1894 {ECO:0000313|EMBL:ABD02849.1};
OS Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium
OS Yellowstone B-Prime).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=321332 {ECO:0000313|EMBL:ABD02849.1, ECO:0000313|Proteomes:UP000001938};
RN [1] {ECO:0000313|EMBL:ABD02849.1, ECO:0000313|Proteomes:UP000001938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA-2-3B'a(2-13) {ECO:0000313|Proteomes:UP000001938};
RX PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA Bhaya D., Grossman A.R., Steunou A.S., Khuri N., Cohan F.M., Hamamura N.,
RA Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT "Population level functional diversity in a microbial community revealed by
RT comparative genomic and metagenomic analyses.";
RL ISME J. 1:703-713(2007).
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DR EMBL; CP000240; ABD02849.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2JKE0; -.
DR STRING; 321332.CYB_1894; -.
DR MEROPS; S11.A01; -.
DR KEGG; cyb:CYB_1894; -.
DR eggNOG; COG2367; Bacteria.
DR HOGENOM; CLU_031960_1_0_3; -.
DR OrthoDB; 9775096at2; -.
DR Proteomes; UP000001938; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001938};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 175..384
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 46607 MW; D79ECC401A5D02C7 CRC64;
MTRARERKGT DPSALAGRRP LPEKSRDPRR PPQPAKNAVP PPEGSKPQTG SGRLLPAPRG
SLLVSRPQPL RLARQKAIAR LRQRAARPRR LRRSPSLGQV LLRGLSLSLI LGLTMAGLSQ
LLQSTTAGRT EQSTTQLGDP PPSAFPSNIL PGEAIPALQE RLAALADQPG LTAGALFWEV
ETGAFAGVRP DQAFPAASVI KIPILLAFFQ AVETGQVRLD EQLTLREDLK GGGAGVLQTR
PLGSQVSALE AATLMITLSD NFATNLIIDR LGGQETLNQK FRQWGLQHTQ ISWWLPDLEG
TNTSSPRDMV WLLSQVEQGR MLNRRSRDRF LDILWRTQRL SYFRPNLGQE VRIAHKTGTL
GSVVGDAGIL DLPNGRRYVA AVWVKRETPN DPRAEGLIAS LSQAAYEFWS APEDPTAKDS
MGSLER
//
