ID Q2JP88_SYNJB Unreviewed; 464 AA.
AC Q2JP88;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN Name=nifE {ECO:0000313|EMBL:ABD01407.1};
GN OrderedLocusNames=CYB_0411 {ECO:0000313|EMBL:ABD01407.1};
OS Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium
OS Yellowstone B-Prime).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=321332 {ECO:0000313|EMBL:ABD01407.1, ECO:0000313|Proteomes:UP000001938};
RN [1] {ECO:0000313|EMBL:ABD01407.1, ECO:0000313|Proteomes:UP000001938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA-2-3B'a(2-13) {ECO:0000313|Proteomes:UP000001938};
RX PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA Bhaya D., Grossman A.R., Steunou A.S., Khuri N., Cohan F.M., Hamamura N.,
RA Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT "Population level functional diversity in a microbial community revealed by
RT comparative genomic and metagenomic analyses.";
RL ISME J. 1:703-713(2007).
CC -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC prosthetic group of nitrogenase (FeMo cofactor).
CC {ECO:0000256|ARBA:ARBA00003171}.
CC -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005155}.
CC -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
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DR EMBL; CP000240; ABD01407.1; -; Genomic_DNA.
DR RefSeq; WP_011432073.1; NC_007776.1.
DR AlphaFoldDB; Q2JP88; -.
DR STRING; 321332.CYB_0411; -.
DR KEGG; cyb:CYB_0411; -.
DR eggNOG; COG2710; Bacteria.
DR HOGENOM; CLU_025876_1_1_3; -.
DR OrthoDB; 9767044at2; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000001938; Chromosome.
DR GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR CDD; cd01968; Nitrogenase_NifE_I; 1.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR000318; Nase_comp1_CS.
DR InterPro; IPR005973; NifE.
DR NCBIfam; TIGR01283; nifE; 1.
DR PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00699; NITROGENASE_1_1; 1.
PE 3: Inferred from homology;
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW ECO:0000256|RuleBase:RU004021};
KW Reference proteome {ECO:0000313|Proteomes:UP000001938}.
FT DOMAIN 46..441
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
SQ SEQUENCE 464 AA; 50689 MW; F34C4DEB1868D49E CRC64;
MPLISRTKVA ELLNETACEH NHKKDGKGKN KVCAEQAKPG GAQGGCAFDG ASIALVPIAD
AAHLVHGPIA CSGNSWGTRG SLSSGPQLYR VGFTTDLSEN EIIFGGEEKL FQAILDLQAK
YQPAAIFVYL TCVTALIGDD VEAVCQRASR QLGIPVIPVN APGFVGSKNL GNRLAGEALL
DYVIGTASPE YTTPRDINLI GEYNIAGELW DVLPLFDELG IRILAKITGD GRYREICTAH
RAKLNVLICA KALLNVGRKM QERYGIPYIE ASFYGLQEMN HCLRAIAQGL KDPELQERTE
ALIERETRAT EAALAPYRQR LAGKRVVLYT GGVKSWSIIS AARDLGMQVT ATSTRKSTEE
DKARIRELLG QDGILLDKGS PQELLKVVER TKADLLIAGG RNQYTALKAR IPFLDINQER
HHAYAGYRGL VNLAREIDAA LHSPIWEQLR RPAPWETPAE EEVG
//
