GenomeNet

Database: UniProt
Entry: Q2KE56
LinkDB: Q2KE56
Original site: Q2KE56 
ID   HIS7_RHIEC              Reviewed;         202 AA.
AC   Q2KE56;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   14-MAY-2014, entry version 54.
DE   RecName: Full=Imidazoleglycerol-phosphate dehydratase;
DE            Short=IGPD;
DE            EC=4.2.1.19;
GN   Name=hisB; OrderedLocusNames=RHE_CH00047;
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251;
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic
RT   redundancy in seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- CATALYTIC ACTIVITY: D-erythro-1-(imidazol-4-yl)glycerol 3-
CC       phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-histidine biosynthesis; L-
CC       histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the imidazoleglycerol-phosphate dehydratase
CC       family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000133; ABC88880.1; -; Genomic_DNA.
DR   RefSeq; YP_467607.1; NC_007761.1.
DR   ProteinModelPortal; Q2KE56; -.
DR   SMR; Q2KE56; 7-189.
DR   STRING; 347834.RHE_CH00047; -.
DR   EnsemblBacteria; ABC88880; ABC88880; RHE_CH00047.
DR   GeneID; 3893191; -.
DR   KEGG; ret:RHE_CH00047; -.
DR   PATRIC; 23081368; VBIRhiEtl108884_0376.
DR   eggNOG; COG0131; -.
DR   HOGENOM; HOG000228064; -.
DR   KO; K01693; -.
DR   OMA; HHIAESC; -.
DR   OrthoDB; EOG60PHGP; -.
DR   BioCyc; RETL347834:GJJ0-47-MONOMER; -.
DR   UniPathway; UPA00031; UER00011.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004424; F:imidazoleglycerol-phosphate dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00076; HisB; 1.
DR   InterPro; IPR000807; ImidazoleglycerolP_deHydtase.
DR   InterPro; IPR020565; ImidazoleglycerP_deHydtase_CS.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR23133:SF2; PTHR23133:SF2; 1.
DR   Pfam; PF00475; IGPD; 1.
DR   SUPFAM; SSF54211; SSF54211; 2.
DR   PROSITE; PS00954; IGP_DEHYDRATASE_1; 1.
DR   PROSITE; PS00955; IGP_DEHYDRATASE_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm;
KW   Histidine biosynthesis; Lyase.
FT   CHAIN         1    202       Imidazoleglycerol-phosphate dehydratase.
FT                                /FTId=PRO_0000336337.
SQ   SEQUENCE   202 AA;  21803 MW;  0CE6106DFD9A86B0 CRC64;
     MAETAASRTG SVARKTNETS ISVSVNLDGT GKSKISTGVG FFDHMLDQLS RHSLIDMEIE
     AKGDLHIDDH HTVEDTGIAI GQAISKALGD RRGITRYASI DLAMDETMTK AAVDLSGRPF
     LVWNVAFSAP KIGTFDTELV REFFQALAQN AGITLHLLNH YGANNHHIAE TCFKAVARAL
     RTATEIDPRQ AGRVPSTKGT LV
//
DBGET integrated database retrieval system