ID   Q2L8H7_LISMN            Unreviewed;       794 AA.
AC   Q2L8H7;
DT   21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   21-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=InlA {ECO:0000313|EMBL:ABC72028.1};
DE   Flags: Fragment;
GN   Name=inlA {ECO:0000313|EMBL:ABC72028.1};
OS   Listeria monocytogenes.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=1639 {ECO:0000313|EMBL:ABC72028.1};
RN   [1] {ECO:0000313|EMBL:ABC72028.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FSLF2318 {ECO:0000313|EMBL:ABC72028.1};
RA   Tsai Y.-H.L., McGann P., Orsi R., Wiedmann M.;
RT   "Evolutionary studies on Listeria monocytogenes lineage III based on
RT   housekeeping and internalin genes.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the internalin family.
CC       {ECO:0000256|ARBA:ARBA00009432}.
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DR   EMBL; DQ347769; ABC72028.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2L8H7; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.1220; -; 1.
DR   Gene3D; 2.60.40.4270; Listeria-Bacteroides repeat domain; 3.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR012569; Inl_IR.
DR   InterPro; IPR047600; InlA.
DR   InterPro; IPR013378; InlB-like_B-rpt.
DR   InterPro; IPR024634; Internalin_N.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR042229; Listeria/Bacterioides_rpt_sf.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   NCBIfam; NF033189; internalin_A; 1.
DR   NCBIfam; TIGR02543; List_Bact_rpt; 3.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR   Pfam; PF09479; Flg_new; 3.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   Pfam; PF12354; Internalin_N; 1.
DR   Pfam; PF12799; LRR_4; 6.
DR   Pfam; PF08191; LRR_adjacent; 1.
DR   SMART; SM00365; LRR_SD22; 15.
DR   SMART; SM00369; LRR_TYP; 11.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR   PROSITE; PS51450; LRR; 13.
PE   3: Inferred from homology;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          766..794
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          706..755
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABC72028.1"
FT   NON_TER         794
FT                   /evidence="ECO:0000313|EMBL:ABC72028.1"
SQ   SEQUENCE   794 AA;  85997 MW;  EF32B69ADCB3C068 CRC64;
     RRKRYVWLKS ILVAILVLGS GVWINTSNGT NAQAATITQD TPINQIFTDT ALAEKMKTVL
     GKTNVTDTVS QTDLDQVTTL QADRLGIKSI DGLEYLNNLT QINFSNNQLT DITPLKDLTK
     LVDILMNNNQ IADITPLANL SNLTGLTLFN NQITDIDPLK NLTNLNRLEL SSNTISDISA
     LSGLTNLQQL SFGNQVTDLK PLANLTTLER LDISSNKVSD ISVLAKLTNL ESLIATNNQI
     SDITPLGILT NLDELSLNGN QLKDIGTLAS LTNLTDLDLA NNQISNLAPL SGLTKLTELK
     LGANQISNIS PLAGLTALTN LELNENQLED ISPISNLKNL TYLTLYFNNI SDISPVSSLT
     KLQRLFFYNN KVSDVSSLAN LTNINWLSAG HNQISDLTPL ANLTRITQLG LNDQEWTNPP
     VKYKVNVSIP NTVKNVTGAL IAPATISDGG SYAEPDITWN LPSYTNEVSY TFNQSVTIGK
     GTTTFSGTVT QPLKAIFNAK FHVDGKETTK EVEAGNLLTE PAKPVKEGYT FVGWFDAQTG
     GTKWNFSTDK MPTNDIDLYA QFSINSYTAT FDNDGVTTSQ TVDYQGLLQE PTAPTKEGYT
     FKGWYDAKTG GDKWDFATSK MPAKNITLYA QYSANSYTAT FDVDGKTTTQ AVDYQGLLKE
     PKTPTKAGYT FKGWYDEKTD GKKWDFATDK MPANDITLYA QFTKNPVAPP TTGGNTPPTT
     NNGGNTTSPS ANIPGSNTTN TSTGNSASTT STMNAYDPYN SKEASLPTTG DSDNALYLLI
     GLLAVGTAVA LTKK
//