ID Q2LX97_SYNAS Unreviewed; 448 AA.
AC Q2LX97;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN ORFNames=SYN_02618 {ECO:0000313|EMBL:ABC78706.1};
OS Syntrophus aciditrophicus (strain SB).
OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC Syntrophus.
OX NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC78706.1, ECO:0000313|Proteomes:UP000001933};
RN [1] {ECO:0000313|EMBL:ABC78706.1, ECO:0000313|Proteomes:UP000001933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB {ECO:0000313|EMBL:ABC78706.1,
RC ECO:0000313|Proteomes:UP000001933};
RX PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA Campbell J.W., Gunsalus R.P.;
RT "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT of microbial growth.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
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DR EMBL; CP000252; ABC78706.1; -; Genomic_DNA.
DR RefSeq; WP_011418723.1; NC_007759.1.
DR AlphaFoldDB; Q2LX97; -.
DR STRING; 56780.SYN_02618; -.
DR KEGG; sat:SYN_02618; -.
DR eggNOG; COG0569; Bacteria.
DR HOGENOM; CLU_046525_0_3_7; -.
DR InParanoid; Q2LX97; -.
DR OrthoDB; 9775180at2; -.
DR Proteomes; UP000001933; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000001933}.
FT DOMAIN 2..129
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 141..225
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 232..354
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 367..448
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 448 AA; 49955 MW; 8BB67F94F777C75D CRC64;
MRIIIVGAGE VGSHLSESLS LEGHEVVLID RNTERIRYLE KKLDVLTIVG NGASAQVLEH
GGIKDTDLFI AVTDIDEVNL VASILAREYH VKHRVARVRN EEFLSPGSPL NETRLGLDLL
INPDRVMAEE ILRLVDLSEA FDFFEFADGQ VVLLGYRIKE NNPICGLTMQ ELGEIRGIYD
FVIVSILRGN QALIPRGPDV IEAGDSIYLT ARRSEIPNVE YLLNLSSKAP KRIFIIGGGR
VGSLVARQME SRRVDVRLVE KDSDRCQKLS EVLEKTILLN LDGMDSRELL EEGIDRADLV
IAVTGDDDVN ILSSLLAKHH GTAKCITRID RPDFIPLLEK LGVDMALSPR LLAAGTILKF
VRRGSIRAVA NILRVDAEVL EMVVPDKPHF RQQPIRKLRF PDRAIMGAVV RKDRVLIPTG
DTILEPKDDV IIFALHDAIP EVELFFEP
//
