ID   Q2M124_DROPS            Unreviewed;       807 AA.
AC   Q2M124; A0A6I8UCF8;
DT   21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   21-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Insulin-like growth factor-binding protein complex acid labile subunit {ECO:0000313|RefSeq:XP_001353249.1};
GN   Name=LOC4813552 {ECO:0000313|RefSeq:XP_001353249.1};
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_001353249.1};
RN   [1] {ECO:0000313|RefSeq:XP_001353249.1}
RP   IDENTIFICATION.
RC   STRAIN=MV2-25 {ECO:0000313|RefSeq:XP_001353249.1};
RC   TISSUE=Whole body {ECO:0000313|RefSeq:XP_001353249.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_001353249.1; XM_001353213.4.
DR   AlphaFoldDB; Q2M124; -.
DR   STRING; 46245.Q2M124; -.
DR   EnsemblMetazoa; FBtr0276463; FBpp0274901; FBgn0076864.
DR   GeneID; 4813552; -.
DR   KEGG; dpo:4813552; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   HOGENOM; CLU_349263_0_0_1; -.
DR   InParanoid; Q2M124; -.
DR   OMA; PTQQITT; -.
DR   Proteomes; UP000001819; Chromosome X.
DR   Bgee; FBgn0076864; Expressed in insect adult head.
DR   ExpressionAtlas; Q2M124; baseline.
DR   GO; GO:0005615; C:extracellular space; IEA:EnsemblMetazoa.
DR   GO; GO:0007474; P:imaginal disc-derived wing vein specification; IEA:EnsemblMetazoa.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:EnsemblMetazoa.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR24373:SF382; FI03225P; 1.
DR   PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR   Pfam; PF13855; LRR_8; 4.
DR   PRINTS; PR00019; LEURICHRPT.
DR   SMART; SM00364; LRR_BAC; 6.
DR   SMART; SM00365; LRR_SD22; 6.
DR   SMART; SM00369; LRR_TYP; 13.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001819}.
SQ   SEQUENCE   807 AA;  89506 MW;  4A4FA17FAB49B38F CRC64;
     MTSLMYAVFH IASLQCSVRP EISPCTCETG KASNYVELSC EKLESFNAIV DTLANKLNPD
     VHTDLKITHS QLDDLEMRSF TDMNFNLYKL RMQWNGLRSL PELPFRGLSN VTYLSVGDNE
     LDEIPKHVLN HMPSLATLDI GRCNIRAVQQ DDLKGIQVVT NLILPSNNIT RLDRGAFPQS
     LLILHLGRNQ IESLNGSLHD LHVLQSLFIN ANNISDLDGE LPDGSRLRLL MAHNNRLERL
     PANMAGMRYL QTIHVHFNRL RSFDRVLRNS QDLEELLAGN NELEYLAQDE FQACGRLDVL
     HLASNHIRSL NSSLLPMVKL TIANFSFNDM EEFSMEELHG LRLLKRLDLS HNRISRLLPS
     TKGVQELVLF ALRLDNNQIV SLDGALAGLG NLRILDLSAN RLEHLLLGDF DGMQRLEILD
     MTGNQLVELK PLETTMLPNL KILKLAFNNI TKLERDFNGL PVLCQANLTN NQITTISSEL
     VTNTRCKNHN VAGKLEIHLD DNPIMCDVRL NELCPLMAVQ DARIRGRSQC FENDQEVCTV
     LPMLYKIDLP LLMTNLKIGG GEDAKPVVQM LVPTLLKTNE ELLPPLIATL GQPLINPVII
     GTTAVGPLPP LLTTTTTPWP VPLKSELERN ETATTTPIPP ITNTTTTAAI VTTTTTPNSQ
     MAATELVTTT APTTTTTSTT TPKPNETLPI ILDIEEPNVV PHADPMPIND TGIAGGELPI
     VPKEADQAVP PVAVEDPLEH DHERDLDHES VAKTEYETVE YIPNLVQPPT PPPSKTNVLE
     EDSDSQANSV HAESAQSLQV PEEPPEE
//