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Database: UniProt
Entry: Q2NJY3
LinkDB: Q2NJY3
Original site: Q2NJY3 
ID   RNC_AYWBP               Reviewed;         237 AA.
AC   Q2NJY3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   14-MAY-2014, entry version 55.
DE   RecName: Full=Ribonuclease 3;
DE            EC=3.1.26.3;
DE   AltName: Full=Ribonuclease III;
DE            Short=RNase III;
GN   Name=rnc; OrderedLocusNames=AYWB_143;
OS   Aster yellows witches'-broom phytoplasma (strain AYWB).
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales;
OC   Acholeplasmataceae; Candidatus Phytoplasma;
OC   Candidatus Phytoplasma asteris.
OX   NCBI_TaxID=322098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AYWB;
RX   PubMed=16672622; DOI=10.1128/JB.188.10.3682-3696.2006;
RA   Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A.,
RA   Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W.,
RA   Hogenhout S.A.;
RT   "Living with genome instability: the adaptation of phytoplasmas to
RT   diverse environments of their insect and plant hosts.";
RL   J. Bacteriol. 188:3682-3696(2006).
CC   -!- FUNCTION: Digests double-stranded RNA. Involved in the processing
CC       of primary rRNA transcript to yield the immediate precursors to
CC       the large and small rRNAs (23S and 16S). Also processes some
CC       mRNAs, and tRNAs when they are encoded in the rRNA operon (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage to 5'-
CC       phosphomonoester.
CC   -!- COFACTOR: Mg(2+) (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Contains 1 DRBM (double-stranded RNA-binding) domain.
CC   -!- SIMILARITY: Contains 1 RNase III domain.
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DR   EMBL; CP000061; ABC65260.1; -; Genomic_DNA.
DR   RefSeq; YP_456339.1; NC_007716.1.
DR   ProteinModelPortal; Q2NJY3; -.
DR   STRING; 322098.AYWB_143; -.
DR   EnsemblBacteria; ABC65260; ABC65260; AYWB_143.
DR   GeneID; 3865836; -.
DR   KEGG; ayw:AYWB_143; -.
DR   PATRIC; 21004222; VBIAstYel136969_0168.
DR   eggNOG; COG0571; -.
DR   HOGENOM; HOG000246808; -.
DR   KO; K03685; -.
DR   OMA; AQKDPKT; -.
DR   OrthoDB; EOG6T1WVS; -.
DR   BioCyc; CPHY322098:GJ7E-150-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   Gene3D; 3.30.160.20; -; 1.
DR   HAMAP; MF_00104; RNase_III; 1.
DR   InterPro; IPR014720; dsRNA-bd_dom.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR000999; RNase_III_dom.
DR   PANTHER; PTHR11207; PTHR11207; 1.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF14622; Ribonucleas_3_3; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SMART; SM00535; RIBOc; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
DR   TIGRFAMs; TIGR02191; RNaseIII; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS00517; RNASE_3_1; 1.
DR   PROSITE; PS50142; RNASE_3_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Endonuclease; Hydrolase; Magnesium;
KW   Metal-binding; mRNA processing; Nuclease; RNA-binding;
KW   rRNA processing; rRNA-binding; tRNA processing.
FT   CHAIN         1    237       Ribonuclease 3.
FT                                /FTId=PRO_1000075721.
FT   DOMAIN        4    130       RNase III.
FT   DOMAIN      154    222       DRBM.
FT   ACT_SITE     49     49       Potential.
FT   ACT_SITE    119    119       By similarity.
FT   METAL        45     45       Magnesium (By similarity).
FT   METAL       116    116       Magnesium (By similarity).
FT   METAL       119    119       Magnesium (By similarity).
SQ   SEQUENCE   237 AA;  26797 MW;  9B65C152553E394B CRC64;
     MKNIQILFQT LNIFPKNLVL YKQALTHSSY SNEQTPPQED NERLEFLGDA IVGLLMADYL
     YSQSKEDEGI MTKKRAQAVC EKSLTIYAQK IELQNYLLLG KGEKNKDFNA KGIMADTFEA
     LFGAIYLDLG YLTAKKVFHN IVLPHLAKTI YIIDFKTQLQ EIVQSEKKTI QYKIVQEQGP
     AHSKNFVAEV YLEKNLLGTG EGSTKKSAEQ KAAQQALSKV AKTKDLIKNK GVKEKEL
//
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