ID Q2NQA8_SODGM Unreviewed; 295 AA.
AC Q2NQA8;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=Hydrogen peroxide-inducible genes activator {ECO:0000313|EMBL:CRL46759.1};
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:BAE75667.1};
GN Name=oxyR_5 {ECO:0000313|EMBL:CRL46759.1};
GN OrderedLocusNames=SG2392 {ECO:0000313|EMBL:BAE75667.1};
GN ORFNames=SGGMMB4_05630 {ECO:0000313|EMBL:CRL46759.1};
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509 {ECO:0000313|EMBL:BAE75667.1, ECO:0000313|Proteomes:UP000001932};
RN [1] {ECO:0000313|EMBL:BAE75667.1, ECO:0000313|Proteomes:UP000001932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Morsitans {ECO:0000313|EMBL:BAE75667.1}, and morsitans
RC {ECO:0000313|Proteomes:UP000001932};
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
RN [2] {ECO:0000313|EMBL:CRL46759.1, ECO:0000313|Proteomes:UP000245838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4 {ECO:0000313|EMBL:CRL46759.1}, and morsitans
RC {ECO:0000313|Proteomes:UP000245838};
RA Goodhead I.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP008232; BAE75667.1; -; Genomic_DNA.
DR EMBL; LN854557; CRL46759.1; -; Genomic_DNA.
DR RefSeq; WP_011412198.1; NZ_LN854557.1.
DR STRING; 343509.SG2392; -.
DR KEGG; sgl:SG2392; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_1_6; -.
DR OrthoDB; 9803735at2; -.
DR BioCyc; SGLO343509:SGP1_RS21715-MONOMER; -.
DR Proteomes; UP000001932; Chromosome.
DR Proteomes; UP000245838; Chromosome sggmmb4_Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08430; PBP2_IlvY; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037404; IlvY_PBP2.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF81; HTH-TYPE TRANSCRIPTIONAL REGULATOR ILVY; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 295 AA; 32727 MW; 5E51B6D0FC070F00 CRC64;
MDIRDLKLFL HLAESRHFGR SSKAMHVSTS TLSRQIQRLE ENVGQTLFLR NNRTVQLTEA
GQQLKEFAQQ TLLQYQQLRH RLGQNGPSLS GELRLFCSVT AAYSHLPPIL DLFRAEHPLV
EIKLTTGDAA NALDKVQSGE ADFGIAGHPE ILPASIDFTP IGEIPMILIA PALPCPVRAR
VKTPQPDWSH TPFILPEHGP ARRRIELWFR SNHISNPLIY ATVAGNEAIV SMVALGCGIA
LIPSVVMDNS PEPVRSRITL LEHGTPVAPL ALGVCAQIKR LHEPLIDAFW QLLER
//
