ID Q2QST6_ORYSJ Unreviewed; 1753 AA.
AC Q2QST6;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN OrderedLocusNames=LOC_Os12g22990 {ECO:0000313|EMBL:ABA97603.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000313|EMBL:ABA97603.1};
RN [1] {ECO:0000313|EMBL:ABA97603.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2] {ECO:0000313|EMBL:ABA97603.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell C.R., Wing R.A., McCombie W.A., Ouyang S.;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABA97603.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell R.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DP000011; ABA97603.1; -; Genomic_DNA.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR45835:SF87; RNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR45835; YALI0A06105P; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1753
FT /note="RNA-directed DNA polymerase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004214401"
FT DOMAIN 590..605
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 840..1019
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1380..1547
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 248..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 216..243
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 249..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..289
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1753 AA; 198953 MW; 85B07F01C7097BA4 CRC64;
MSWHRAGVLL LGAQSCLPVP GVLAVGGIGS VLLSMARMGW KLCHVFRLYT VVMAGSVTRR
GLDMTGFVLE LRGMCVVLGY PHGVDYQGRP LPEQEGDDAE PHAAWEVTAV ILVGSPERTS
LAVTAGGDSF PAACQSAALL AIGTLHQRYP DELQHSPYRY HPRRGGARDY ATFRDASSED
DATIVHLARM VEAYDAARID FHQMVRRGMV ENNMKILELR QENLQLKKDL DAVEAQLHQL
KIAQGEMVTT RRNAATGDGN QPEGSNHNNH QGNPPPPPPP PPPPPPDTNA ILTQILAQQA
NMMTAFLHHL QNPPQHNAPP PPPQHSKLAE FLRIRPPTFS SSNNPVDALD WLHAVGKKLD
TVQCSDEEKV IFAAHQLQGP ASLWWDHFQA TQPEGQPITW ARFTAAFQRT HVPAGVVALK
KREFRELKQG NCSVMEYLHE FNNLARYAPE DVREDEEKQE KFLAGMDPEL SVRLVSGDYP
DFQRLVDKSI RLEAKHKELE SHKRRLANFR NQQGANQRVR YTNPYPGGSS SQQQQQQQQP
RSAPRPQFVV RVPQPQQQQN QQGTRAPRPP TPAVQPGQGR RDAQGQQRLC FNCFEPGHFA
DKCPKPRRQQ GQAPPRSNNG GKDVIRGRVN HVTAEDVLTT PDVIVGTFLI HSIPATILFN
SGASHSFISV PFVGRNQLGV ERLRNPLLIT TPGGVMTAKY YSPAVPIEIQ GIPFPSDLIL
LDTKNLNVIL GMNWLAQFQG VVDCARRTVT LYRGPEQPVV FFAPPTSVSS SELHQIGLSE
IPIVREFGDV FPEELPGMPP KREIEFWIDL APGTTPLYKR PYRMAANELA EVKKQLEELK
EKGYIRPSTS PWGAPVIFVE KKDKTKRMCV DYRALNEVTI KNKYPLPRID DLFDQLKGAT
VFSKIDLRSG YHQLRIREED IPKTAFTTRY GLYEFTVMSF GLTNAPAFFM NLMNKVFMEY
LDKFVVVFID DILIYSQSEE DHQHHLRLVL GKLREHQLYA KLSKCEFWLS EVKFLGHVIS
AKGVAVDPET VTAVTDWKQP KTVTQVRSFL GLAGYYRRFI ENFSKIARPM TQLLKKEEKF
VWSPQCEKAF KTLKEKLVAS PVLILPDTRK DFMVYCDASR QGLGCVLMQD GHVVAYASRQ
LRPHEGNYPT HDLELAAVVH ALKIWRHYLI GNRCEIYTDH KSLKYIFTQS DLNLRQRRWL
ELIKDHDVGI HYHPGKANVV ADALSRKSHC NTLNVRGIPP ELSQQMAALN LSIVSRGFLA
ALEAKPTLLD QIREAQKNDP DMHGLLKNMK QGKAAGFTED EHGTLWNGNR VCVPDNRELK
QLILQEAHES PYSIHPGSTK MYLDLKEKYW WVSMKREIAE FVALCDVCQR VKAEHQRPAG
LLQPLQVPEW KWDEIGMDFI TGLPKTQGGY DSIWVVVDRL TKVARFIPVK TTYGGNKLAE
LYFARIVSLH GVPKKIVSDR GSQFTSHFWK KLQEELGTRL NFSTAYHPQT DGQTERLNQI
LEDMLRACVL DFGKTWDKSL PYAEFSYNNS YQASIQMAPY EALYGRKCRT PLLWDQVGES
QVFGTDILRE AEAKVRTIRD NLKVAQSRQK SYADNRRRDL EFAVDDFVYL RVTPLRGVHR
FQTKGKLAPR YVGPFRIVAR RGEVAYQLEL PASLGNVHDV FHVSQLKKCL RVPSEQADSK
QIEVREDLTY VERPVKILDT MERRTRNRVI RFCKVQWSNH AEEEATWERE DELKAAHPDL
FASSSESRGR DSV
//
