ID ZHD3_ORYSJ Reviewed; 329 AA.
AC Q2QW44; Q0IPF6;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 3.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=Zinc-finger homeodomain protein 3;
DE Short=OsZHD3;
GN Name=ZHD3; OrderedLocusNames=Os12g0208900, LOC_Os12g10630;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18713354; DOI=10.1111/j.1744-7909.2008.00681.x;
RA Hu W., dePamphilis C.W., Ma H.;
RT "Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini
RT zinc finger gene families.";
RL J. Integr. Plant Biol. 50:1031-1045(2008).
CC -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC instead of 3 extra amino acids inserted in the loop between helix 1 and
CC helix 2.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA96146.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF29409.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DP000011; ABA96146.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008218; BAF29409.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014968; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015618832.1; XM_015763346.1.
DR AlphaFoldDB; Q2QW44; -.
DR SMR; Q2QW44; -.
DR PaxDb; 39947-Q2QW44; -.
DR GeneID; 4351766; -.
DR KEGG; osa:4351766; -.
DR eggNOG; ENOG502QSB4; Eukaryota.
DR InParanoid; Q2QW44; -.
DR OrthoDB; 449482at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006455; Homeodomain_ZF_HD.
DR InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR NCBIfam; TIGR01565; homeo_ZF_HD; 1.
DR NCBIfam; TIGR01566; ZF_HD_prot_N; 1.
DR PANTHER; PTHR31948; ZINC-FINGER HOMEODOMAIN PROTEIN 2; 1.
DR PANTHER; PTHR31948:SF155; ZINC-FINGER HOMEODOMAIN PROTEIN 3; 1.
DR Pfam; PF04770; ZF-HD_dimer; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51523; ZF_HD_DIMER; 1.
PE 3: Inferred from homology;
KW DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..329
FT /note="Zinc-finger homeodomain protein 3"
FT /id="PRO_0000426039"
FT ZN_FING 74..123
FT /note="ZF-HD dimerization-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT DNA_BIND 193..256
FT /note="Homeobox"
FT REGION 24..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 245
FT /note="Required for DNA-binding"
FT /evidence="ECO:0000250"
SQ SEQUENCE 329 AA; 34952 MW; B4822362A5CB63D6 CRC64;
MDLSGAQGEL PLPMHAAASP YLGLHHDHHH HHGGGGGGGG MNGRHMSPPT PPAAAEESKA
VVVVSSSATA AARYRECLKN HAAAIGGSAT DGCGEFMPGG EEGSLDALRC SACGCHRNFH
RKELDAAAAP PLHHHHHQLL GVGAHPRGHG HHHHHLLVAA LPPPTRMVMP LSAMHTSESD
DAAARPGGGA AARKRFRTKF TAEQKARMLG FAEEVGWRLQ KLEDAVVQRF CQEVGVKRRV
LKVWMHNNKH TLARRHLHPS PAAAAGDDDD DGAPPPHPDP RRRELAAAAA PPPAPVTQHI
KKSVDNKSLI SSLAALHCIA LLLFHQIDA
//
