ID Q2SID3_HAHCH Unreviewed; 743 AA.
AC Q2SID3;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Predicted helicase {ECO:0000313|EMBL:ABC29591.1};
GN OrderedLocusNames=HCH_02813 {ECO:0000313|EMBL:ABC29591.1};
OS Hahella chejuensis (strain KCTC 2396).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae; Hahella.
OX NCBI_TaxID=349521 {ECO:0000313|EMBL:ABC29591.1, ECO:0000313|Proteomes:UP000000238};
RN [1] {ECO:0000313|EMBL:ABC29591.1, ECO:0000313|Proteomes:UP000000238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2396 {ECO:0000313|EMBL:ABC29591.1,
RC ECO:0000313|Proteomes:UP000000238};
RX PubMed=16352867; DOI=10.1093/nar/gki1016;
RA Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G.,
RA Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K.,
RA Oh T.K., Kim J.F.;
RT "Genomic blueprint of Hahella chejuensis, a marine microbe producing an
RT algicidal agent.";
RL Nucleic Acids Res. 33:7066-7073(2005).
CC -!- SIMILARITY: In the N-terminal section; belongs to the CRISPR-associated
CC nuclease Cas3-HD family. {ECO:0000256|ARBA:ARBA00006847}.
CC -!- SIMILARITY: In the central section; belongs to the CRISPR-associated
CC helicase Cas3 family. {ECO:0000256|ARBA:ARBA00009046}.
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DR EMBL; CP000155; ABC29591.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2SID3; -.
DR STRING; 349521.HCH_02813; -.
DR KEGG; hch:HCH_02813; -.
DR eggNOG; COG1203; Bacteria.
DR eggNOG; COG1418; Bacteria.
DR HOGENOM; CLU_010123_0_0_6; -.
DR OrthoDB; 9810236at2; -.
DR Proteomes; UP000000238; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd09641; Cas3''_I; 1.
DR CDD; cd17930; DEXHc_cas3; 1.
DR Gene3D; 1.10.3210.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006483; CRISPR-assoc_Cas3_HD.
DR InterPro; IPR038257; CRISPR-assoc_Cas3_HD_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR006474; Helicase_Cas3_CRISPR-ass_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01587; cas3_core; 1.
DR NCBIfam; TIGR01596; cas3_HD; 1.
DR PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51643; HD_CAS3; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ABC29591.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000238}.
FT DOMAIN 13..176
FT /note="HD Cas3-type"
FT /evidence="ECO:0000259|PROSITE:PS51643"
FT DOMAIN 232..402
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 743 AA; 83245 MW; BD170D7017217320 CRC64;
MKMFYAHSTP DTSKQDWQLL SEHLSEVGRL AKKFAAVFGC GVENLADISG LLHDLGKYTD
EFQRRLTGET LRVDHATAGA KLVVEKYQSL GYLLAYAIAG HHAGLANGVN GVNRTSLEDR
LKSETYKLSE VWRSELNIPE QLPLPTRFHA RQNRNFFQLA FLTRMLFSCL VDADFLDTEA
FYLQAEGESN SRGEYPSLAD LKPELDSFLS GFKDEGKPVN RRRREILQTV RCNAELDPGL
FSLTVPTGGG KTLASLAFAL DHALMHKLER VIYVIPFTSI VEQNAAVFRQ ALGKRGEGAV
LEHHSAFIED RSKDPEAREK LKLAMENWDA PIVVTTAVQF FESLFADRPS RCRKLHNIAN
SAVILDEAQT LPLKLLKPCV AALDELALNY RTSIVLCTAT QPALHECDNV EDSFVGGFRN
VRELAPNPEQ LYRDFKRVSV RHIGVLDDEA LTSMLLERKQ ALCIVNNRRH AKAVFESIRS
EPGARHLSTL MCAKHRSQVL AQIRKDLKQG KPCRLVSTSL IEAGVDIDFP TVLRAEAGLD
SIAQAAGRCN REGMLPADEC EVLVFNPANE DWAPPVELEQ FASVSRGVMR HHADPLSLAA
IEDYFQHLYW RKEKELDAHD LLGLIASAGI KGLPFETLSS KFRLIESQQM PVIIPFDDIA
RKGLDALDYA EGCVGISRCL QPYIVQIPQV AYQALFDAGA IVAKAEERFE QQFVYLANMD
LYDKECGLSW DNPTFIRAEK QVW
//
