ID Q2TGP4_CHLTH Unreviewed; 975 AA.
AC Q2TGP4;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Polymorphic membrane protein A {ECO:0000313|EMBL:AAX76545.1};
GN Name=pmpA {ECO:0000313|EMBL:AAX76545.1};
OS Chlamydia trachomatis.
OC Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=813 {ECO:0000313|EMBL:AAX76545.1};
RN [1] {ECO:0000313|EMBL:AAX76545.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HAR-13 {ECO:0000313|EMBL:AAX76545.1};
RX PubMed=16352844; DOI=10.1128/JB.188.1.275-286.2006;
RA Gomes J.P., Nunes A., Bruno W.J., Borrego M.J., Florindo C., Dean D.;
RT "Polymorphisms in the nine polymorphic membrane proteins of Chlamydia
RT trachomatis across all serovars: evidence for serovar Da recombination and
RT correlation with tissue tropism.";
RL J. Bacteriol. 188:275-286(2006).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004416}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004416}; Extracellular side
CC {ECO:0000256|ARBA:ARBA00004416}. Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004191}.
CC -!- SIMILARITY: Belongs to the PMP outer membrane protein family.
CC {ECO:0000256|ARBA:ARBA00007542}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY884090; AAX76545.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2TGP4; -.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR011427; Polymorphic_membr_middle.
DR InterPro; IPR003368; POMP_repeat.
DR NCBIfam; TIGR01376; POMP_repeat; 4.
DR PANTHER; PTHR19862; WD REPEAT-CONTAINING PROTEIN 48; 1.
DR PANTHER; PTHR19862:SF14; WD REPEAT-CONTAINING PROTEIN 48; 1.
DR Pfam; PF02415; Chlam_PMP; 5.
DR Pfam; PF07548; ChlamPMP_M; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452}.
FT DOMAIN 699..975
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
SQ SEQUENCE 975 AA; 105655 MW; 6F7F43161840EA7B CRC64;
MNRVIEIHAH YDQRQLSQSP NTNFLVHHPY LTLIPKFLLG ALIVYAPYSF AEMELAISGH
KQGKDRDTFT MISSCPEGTN YIINRKLILS DFSLLNKVSS GGAFRNLAGK ISFLGKNSSA
SIHFKHININ GFGAGVFSES SIEFTDLRKL VAFGSESTGG IFTAKEDISF KNNHHIAFRN
NITKGNGGVI QLQGDMKGSV SFVDQRGATI FTNNQAVTSS SMKHSGRGGA ISGDFAGSRI
LFLNNQQITF EGNSAVHGGA IYNKNGLVEF LGNAGPLAFK ENTTIANGGA IYTSNFKANQ
QTSPILFSQN HANKKGGAIY AQYVNLEQNQ DTIRFEKNTA KEGGGAITSS QCSITAHNTI
IFSDNAAGDL GGGAILLEGK KPSLTLIAHS GNIAFSGNTM LHITKKASLD RHNSILIKEA
PYKIQLAANK NHSIHFFDPV MALSASSSPI QINAPEYETP FFSPKGMIVF SGANLLDDAR
EDVANRTSIF NQPVHLYNGT LSIENGAHLI VQSFKQTGGR ISLSPGSSLA LYTMNSFFHG
NISSKEPLEI NGLSFGVDIS PSNLQAEIRA GNAPLRLSGS PSIHDPEGLF YENRDTAASP
YQMEILLTSD KTVDISKFTT DSLVTNKQSG FQGAWHFSWQ PNTINNTKQK ILRASWLPTG
EYVLESNRVG RAVPNSLWST FLLLQTASHN LSDHLCNNRS LIPTSYFGVL IGGTGAEMST
HSSEEESFIS RLGATGTSII RLTPSLTLSG GGSHMFGDSF VADLPEHITS EGIVQNVGLT
HVWGPLTVNS TLCAALDHNA MVRICSKKDH TYGKWDTFGM RGTLGASYTF LEYDQTMRVF
SFANIEATNI LQRAFTETGY NPRSFSKTKL LNIAIPIGIG YEFCLGNSSF ALLGKGSIGY
SRDIKRENPS TLAHLAMNDF AWTTNGCSVP TSAHTLANQL ILRYKACSLY ITAYTINREG
KNLSNSLSCG GYVGF
//
