ID Q2TWQ6_ASPOR Unreviewed; 835 AA.
AC Q2TWQ6;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=mRNA decay factor PAT1 domain-containing protein {ECO:0000259|Pfam:PF09770};
GN ORFNames=AO090010000464 {ECO:0000313|EMBL:BAE66317.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE66317.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE66317.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the PAT1 family.
CC {ECO:0000256|ARBA:ARBA00009138}.
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DR EMBL; AP007175; BAE66317.1; -; Genomic_DNA.
DR RefSeq; XP_001827450.1; XM_001827398.1.
DR AlphaFoldDB; Q2TWQ6; -.
DR STRING; 510516.Q2TWQ6; -.
DR EnsemblFungi; BAE66317; BAE66317; AO090010000464.
DR GeneID; 5999584; -.
DR KEGG; aor:AO090010000464; -.
DR VEuPathDB; FungiDB:AO090010000464; -.
DR HOGENOM; CLU_012622_1_0_1; -.
DR OMA; YLEHSGH; -.
DR OrthoDB; 2786412at2759; -.
DR Proteomes; UP000006564; Chromosome 8.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR InterPro; IPR039900; Pat1-like.
DR InterPro; IPR019167; PAT1_dom.
DR PANTHER; PTHR21551:SF0; PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A; 1.
DR PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR Pfam; PF09770; PAT1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 1..832
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 92451 MW; 26D2422613844BF3 CRC64;
MSFFGFDTTL PRDRAPGGGQ KGIFDTPDPF AEVARARLAG HFRDNDDDDV IDFEDTYDGL
GDQLDDDQDA FNDDTFGGNM GTGAVGKDFD FFGKTAQVAD VIGEEQVRYS LQKPQAPAAA
PATEVPVATS TVAQQPKRTG YEKYSDPDYI PDLQAKSSVW NLQKQPEPAP APAVQPVAQP
AVQARKMLSL EEVEAQLRHQ GPGPAPGLPP VSLPHSMAEA LHHLQRPQQI PGFPDGFPQL
PPEILQAQFA RGVPPAQMLH HPQMAPEPYP PPNLPLHLLQ NANLPQHLVQ SQHQAPPRGQ
RTQQQQQQQQ QAPPPMPQNV PQGPKGTNGT LPLITNPQQL MQLTEEQRVA YLMEDAKRAK
RNHKIFLLSK GNGLMTPQDK NFITRIQLQQ LVAAAGNVAD ADLEAVLAED FYYQVYSQIR
GAPRQHPHQP LGHFAQTYLL QTGNRLGGHG SRRQAQSADN HMQRMQQQVQ RAVEAAKAKP
KNKQLIIEGS LGKISFSNAK TPKTMLNIKR PETSEGIKAA KKPHTDLSLS DRKSILTNIE
NVYGTLMELE DMERTMPPPP NEGDAEAIQE HMEWRQKVRS LNQKLWQALK VMEPIVPNTN
TPHPFIAFLS YPKGKKAIPR IFRHIDQEQR VTILTMIVVH LDSLDVVRNG QPAPGEPQPS
LPVREAIDLF SQAVMPSLLG YVNEAPFNII IGLLGLVIAQ THVHMVAKTR IGLGILTMLL
SRAEIVKEAG QAAERDWQQW VEKFNILFDT LEPTFAEIFP GSINAGDDMY VWQFLAAVGI
GASPEQQQRL VIAVKDRVME TVAYSKTLPA DMASQRLGNV NLFMRAIGLD VELLG
//
