ID Q2TYS8_ASPOR Unreviewed; 340 AA.
AC Q2TYS8;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=NADP-dependent oxidoreductase domain-containing protein {ECO:0000259|Pfam:PF00248};
GN ORFNames=AO090103000125 {ECO:0000313|EMBL:BAE65595.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE65595.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE65595.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SIMILARITY: Belongs to the aldo/keto reductase family. Aldo/keto
CC reductase 2 subfamily. {ECO:0000256|ARBA:ARBA00038157}.
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DR EMBL; AP007174; BAE65595.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2TYS8; -.
DR EnsemblFungi; BAE65595; BAE65595; AO090103000125.
DR VEuPathDB; FungiDB:AO090103000125; -.
DR HOGENOM; CLU_023205_2_0_1; -.
DR OMA; RATIHND; -.
DR OrthoDB; 5357470at2759; -.
DR Proteomes; UP000006564; Chromosome 8.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd19079; AKR_EcYajO-like; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43364:SF15; ARYL-ALCOHOL DEHYDROGENASE AAD16-RELATED; 1.
DR PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 12..330
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 340 AA; 39027 MW; E65F591A5E8748CC CRC64;
MQLGKSGLKV SKIILGCMSY GSSEWQSWVL NEKDALPLLK HAYDKGINTW DTADIYSHGR
SEEIIGKFLR QEQIPRDRVV IMTKFYFGVD DQGRQPPNRA TIHNDGQEWV NRVGLSRKHI
FDAVEASVRR LGTYIDVLQI HRLDRDTPRK EIMKALNDVV ESGKVRYIGA SSMAAWEFQS
LQNIALQNGW HQFISMQNLH NLIHREEERE MIPYCLDTGV GLIPWSPLAR GVLARPWDSR
STIRETTDTS LKSIIRDRES LADKSIIDRV EEVARRRGIT MSQVAIAWSL SHRTENPILG
LNSKDRIDEA VAAIGVRLTE DEKRYLEELY IPKSIHPSER
//
