ID Q2UHE0_ASPOR Unreviewed; 1049 AA.
AC Q2UHE0;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=AO090023000484 {ECO:0000313|EMBL:BAE59025.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE59025.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE59025.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
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DR EMBL; AP007157; BAE59025.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UHE0; -.
DR STRING; 510516.Q2UHE0; -.
DR EnsemblFungi; BAE59025; BAE59025; AO090023000484.
DR HOGENOM; CLU_003613_0_0_1; -.
DR OMA; NSFMRIV; -.
DR OrthoDB; 1386366at2759; -.
DR Proteomes; UP000006564; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR35859:SF4; MEMBRANE CHANNEL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11300)-RELATED; 1.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 337..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 344..493
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 39..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..70
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..741
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..910
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1049 AA; 118197 MW; B3ED606F8F4C0972 CRC64;
MLASLLRPKK RRVYAERSPF SSPYTTRDLP WPFLQRGSEE AQYEEIRGND DADENVDDGE
EDESGDEDDG PFESSPLLPI FSASHLDTLP VYDITHTIRA LIAARCETTL SWDQLRSPQI
SQFLVKPIQQ QIRAFHFSRA TLYALLTNCL QFNKEVHLNP GNSGTSQTRA MVSELLAIKL
LREYTTRELI DALSYEFFPL QGQSLPGGSQ QPPGWTPTAG NKRLPGVARI SCLEVAIRAQ
AKRFLSHPLV VQQLEAIWAG TIVFHSAADY LHRSPTRVSH SAGPTYGTTV TATTPNPFAG
KLSPRSAELR RSVTLYDPRD ASLFKLSRLR VPRYRQFLST LSFAVLLALF LAVLDQRRVH
ISALEVVFWF WSAGFMLDEL VGFNEQGFSL YLMSFWNLFD LGILFLLFCY YCLRLYGAFM
PFTRKQAVAD QAYDILAANA VLLFPRLFSI LDHYRYFSQL LIAFRIMASD LVAVFFLIII
ACSGFFVAFT LSFGSGEDRS PGSIARFKAF SSRAPRLVRE PSVATYQKDR ALEEVFRRPF
HGETMEPVRE IDQRKTNKIV KNWMQTMGPG PANPPDEQDS DEVSQLEKRP QRPRHFSRRR
LTRSLRDFTE SNRSVVSNPE DHVTYIASSP ATPRAGRDFM ASTRRRQLSR HTGMEGDVEL
TSDGHEDQSN GKSSDDEDTP KDESPGKATP KFYSSRSSTA KVKSRRNSPV RRVKHHSRSY
SGATMLYRPL STTSNGEETE APTIPVRSRA ETPDHADWAA RSTSADRWAM RRHSTDGRSR
NVTMPISNPM SVPEFGHFLA PGPRYSERGP DPILHGLGSD IGDNKAIASG FVGGAPSSLT
TQMAYATGGM RRPDSSHSSQ DILSKLVLAR MNNIEEGFRE VIREMKDLRR EGTSRSQSGP
DESKGNQREK KRTEKKGKKP NPRSRRSKTG SEEQSLLLLS DADTLLYIDP PPQRSCASAL
PRSSESIPHR IRSQKLLETG SNYFKDLFQP RAQARTISRR GLGGKLTNEI HHRAENQRSH
NILALRFGEC SSHRVPSRNC LQNRLWSTA
//
