ID Q2UIH5_ASPOR Unreviewed; 653 AA.
AC Q2UIH5;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Hydrolase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AO090023000053 {ECO:0000313|EMBL:BAE58640.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE58640.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE58640.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; AP007157; BAE58640.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UIH5; -.
DR STRING; 510516.Q2UIH5; -.
DR CAZy; GH2; Glycoside Hydrolase Family 2.
DR EnsemblFungi; BAE58640; BAE58640; AO090023000053.
DR VEuPathDB; FungiDB:AO090023000053; -.
DR HOGENOM; CLU_009935_3_1_1; -.
DR OMA; PQCGSPF; -.
DR OrthoDB; 19834at2759; -.
DR UniPathway; UPA00280; -.
DR Proteomes; UP000006564; Chromosome 3.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 133..238
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 250..331
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 373..504
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT REGION 44..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 73030 MW; E50E13F3D972D404 CRC64;
MPKTSCPVLS SVINMYFAGS SLVLLLATHA LAAVPAALHQ NKARQATPYA VKEPPLTTPW
TDKAGTDPWP EYPRPQLERS EWKNLNGIWQ YQDAQSLAAL DSPPFGQPLA HEVLVPSCLE
SGLSGIQGKD TLYSWFTTQF TVPQSFKDQN VLVNFAAVDY EATVFVNGKK AGFHRGGYFH
FAFDITEFVN RDGENELLVF VHDPTDSGDD VIPIGKQRLV PAHIFYTPCS GIWQSVWIEA
APANHITRLD LAADMNGKVT VTANTATTSG SPVEVKVYDG DEEVGSGQGT SDQTFDFVVD
GVELWSPDSP KLYNVTVTMG DEEVHSYVGF RTIAKGKVDG VVRPLLNGEF IFMFGTLDQG
YWPDGLYTPP TREAMVYDLK FLKDLGFNMV RKHIKVEPAL FYRACDELGL LVIQDMPSAR
PLSRPDPCAT SDIIPNASQQ EEFSRQLEVL VNQFKSYPSI IAWVIYNEGW GQITSYYPEF
ELTDRVKELD PSRLVDSTSG WIDHGAGDFS DNHHYANPQC GTPFYSLSSS PHDPSRIGFQ
GEFGGIGHNV SIENLWNVQE AINHINETYE IDETLEAWNY RGHILLTEFE DQVRRFECSG
GVWTQTTDVE GEVNGLMTYD RRVKRVDEEQ WKNDIQALYD AAAKRGAPSR RKM
//
