ID Q2URR8_ASPOR Unreviewed; 1937 AA.
AC Q2URR8;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE RecName: Full=Sensor histidine kinase/response regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=AO090005000715 {ECO:0000313|EMBL:BAE55747.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE55747.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE55747.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
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DR EMBL; AP007151; BAE55747.1; -; Genomic_DNA.
DR STRING; 510516.Q2URR8; -.
DR EnsemblFungi; BAE55747; BAE55747; AO090005000715.
DR HOGENOM; CLU_000263_0_0_1; -.
DR OMA; WGQKATF; -.
DR OrthoDB; 1222064at2759; -.
DR Proteomes; UP000006564; Chromosome 1.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF74; HISTIDINE KINASE D5; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 988..1042
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1237..1463
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1794..1916
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 1..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 831..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1459..1553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1573..1621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..450
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1473..1552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1573..1618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1846
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1937 AA; 213891 MW; E28861B55B9777BE CRC64;
MRTTPLPSPA EAPSPVAAPH PHLRGSPQST SDLVSSRNVG CTADGNVPIE NNIWKANSQS
PSALHEQTAT PYCASPPTKK ENSDSGKGPQ EDQGRSLQTL KELRRQMEEL LVYQQMQQSQ
TQNASATREP TSSQADHVSS SYESSRKRRI SNVSSPRIAP LPTDAMPSAS YSDSTGSGGT
IRAADLTPEN IPGQTPSYPF PRMQHQSAPR STQDPTHSHN PFKLTLPAER LKVHKTSSQP
ADERQPTSMK TPTSHSVFLP PQYKPVAEDP TYSTPNLYDL TLQLNADPGL DAWWANVVHI
LQENYGAERA SLAIPGDATD LENVPWGQKA VFDRNLEGYE RETIQNQQSQ NEATGTSEGS
TKGVANPEKR KGESTTESLA NGSGAAKLLK RPSLLARHSF AGFGKERKLS TWQDSETLPQ
EHKAKNESKR VQISNENPDV TGTAQSQASA TTYQGHTVPF TQSFDPISPT QYNHRQVVFP
TSRPLEVETD PLIKRTGVVK LFGRTGPVVL TREYSENTAA KQSDGDVQTP EDVVQVTPTA
EPVRPSNKEH AIRSRSVSNP AASGLHAPRV PLMEFYDEYE QIPPSPWSQS PAPSPAPRAH
AEQNPFFSSH TVDEGAFAKH PPQHDYSNLN PLEAIGVDLA KSVIHIPLLH AGRSKPTPPS
TLRFPVAVIS ILSPIIPYPA NLRQSLACLI PHLTTSFCLA QHYSQLERQF ASRLEAPRYG
HLLGLGGTFS DESSELELVA GLSGHVNYTI ADDGSLEARA SLSSPDERSN SAKPSPSGIG
TPGLDLGSIG AEVPSVLGES PGFPTKLGAD AVDSYFNVQQ LKGLRDALTH HRNRLSKPRQ
NATTSTPTSP GRLLGKLPTD EDGTTAQDPT AAQASPSQEF RAPPVISPTQ SSSRHPSANS
FYAQLPRELP RPFTDTVAQL MLNSVPLHIF LAKPQSGEVI WTNSKFDAYR RSQPQEQKLR
DPWQNIHSSE REHVSQEWAN ALRTGSQFTE RVRVKRFNDE SAYRWFIFRA NPLLSSTGEV
LYWIGSFLDI HEQHIAELKA AQEREKFAID AKYRAFSNSI PQIVFEATEF RGLIFVNEQW
HLYTGQKLEE ALNFGFAKHL HPDDLEKCGV LSVYLSESQK ENTVSGLDTT LQERHLANGV
TPALEELVRR GVASVQKDEN GRVFYSTEIR LRSKGADFRW HLVRLVRVET SSFGSGEASW
YGTCTDINDR KNLERELNKA MQQLNNQMES KTKFFSNMSH EIRTPLNGIL GTIPFILDTH
LDTDQRRMLD TIQNSSTNLR ELVDNILDVS RVEAGKMSLV NSWFHVRSVI EDVIDTVSSR
AIDKGLEINY LMDVDVPPMV IGDRFRIRQV LINLVGNAVK FTSQGEIHIR CSINHGTATL
SKETELLLNF DVVDTGKGFS ARDAERLMQR FSQLGQNGSQ QHAGSGLGLF LSKQLVEMHG
GRLTPSSKEG QGAKFSFYVK VDAPPPPSPD EPRLVRQSSS MSEGLGIQSK PSSLQKMLFS
SRDSIDSKGP DTSDISSVLD SPLSQPPSSS DPSARFTSNS FSERSSVSSA LPTPELHAVD
PLTKVDTAKL INTDVSSQAR PTTTASSSSD TIRPVARPSS STSRELSLST TSAPVDAGSD
APVSQDPYSI LILCPLDNTR KAIKQHIEQV VPHEIPFSII SLPDVEDWKD SMNDESSAKI
THLVLNLPSV EDVQDVIQYV LDCDSASAPT LVIISDLYQK RQINSKIKEL SASGGRVYTV
PKPVKPSAFS AIFDPDNRRD LSKDRNQDMA REINNNFKTM SKMVKEVIGN KGYRILLVED
DETNRMVMLK YLDKIKVMAE TASNGQECTE MVFSKEPGYY SLIICDIQMP MKNGYETCRD
IRGWELKNHY PQIPIMALSA NAMTDQIEDA ARAGFNDYVT KPIKHNELGK MMMGLLDPSR
PLLLLRDRLR RDNHRED
//
