ID Q2UXP8_9ENTE Unreviewed; 151 AA.
AC Q2UXP8;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
DE Flags: Fragment;
GN Name=pheS {ECO:0000313|EMBL:CAJ01803.1};
OS Enterococcus silesiacus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=332949 {ECO:0000313|EMBL:CAJ01803.1};
RN [1] {ECO:0000313|EMBL:CAJ01803.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 23084 {ECO:0000313|EMBL:CAJ01804.1}, and Type strain: LMG
RC 23085 {ECO:0000313|EMBL:CAJ01803.1};
RA Hoste B.A.D.;
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAJ01803.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 23084 {ECO:0000313|EMBL:CAJ01804.1}, and Type strain: LMG
RC 23085 {ECO:0000313|EMBL:CAJ01803.1};
RA Svec P., Vancanneyt M., Sedlacek I., Naser S.M., Snauwaert C., Lefebvre K.,
RA Hoste B., Swings J.;
RT "Enterococcus silesiacus sp. nov. and Enterococcus termitis sp. nov.";
RL Int. J. Syst. Evol. Microbiol. 56:577-581(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) +
CC L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668,
CC Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00000395};
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DR EMBL; AM039970; CAJ01803.1; -; Genomic_DNA.
DR EMBL; AM039971; CAJ01804.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UXP8; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR PANTHER; PTHR11538:SF41; PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:CAJ01803.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|EMBL:CAJ01803.1}.
FT DOMAIN 1..108
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAJ01803.1"
FT NON_TER 151
FT /evidence="ECO:0000313|EMBL:CAJ01803.1"
SQ SEQUENCE 151 AA; 16954 MW; 8E54428EAF4C4D0C CRC64;
DTFYISDEIL IRTHTSPVQA RTMEKHDFSK GALRMISPGK VFRRDTDDAT HSHQFHQIEG
LVIDKNITMG DLKGTLEVVM KKMFGEDRKI RLRPSYFPFT EPSVEVDVSC FKCGGAGCNV
CKQTGWIEIL GAGMVHPDVL SMSGIDPNEY T
//
