ID Q2VWB8_GADMO Unreviewed; 223 AA.
AC Q2VWB8;
DT 10-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 10-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative granzyme {ECO:0000313|EMBL:AAV73911.1};
DE Flags: Fragment;
OS Gadus morhua (Atlantic cod).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus.
OX NCBI_TaxID=8049 {ECO:0000313|EMBL:AAV73911.1};
RN [1] {ECO:0000313|EMBL:AAV73911.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:AAV73911.1};
RX PubMed=16413608; DOI=10.1016/j.dci.2005.10.014;
RA Wernersson S., Reimer J.M., Poorafshar M., Karlson U., Wermenstam N.,
RA Bengten E., Wilson M., Pilstrom L., Hellman L.;
RT "Granzyme-like sequences in bony fish shed light on the emergence of
RT hematopoietic serine proteases during vertebrate evolution.";
RL Dev. Comp. Immunol. 30:901-918(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY661884; AAV73911.1; -; mRNA.
DR AlphaFoldDB; Q2VWB8; -.
DR MEROPS; S01.136; -.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24271:SF81; GRANZYME B; 1.
DR PANTHER; PTHR24271; KALLIKREIN-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 13..203
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAV73911.1"
SQ SEQUENCE 223 AA; 24646 MW; DAE843A6B36D0538 CRC64;
ALSLRGQVQT GKIIVGHPAV PHSRPYMVLL GREMWKNETK YCDGFLISDE FVMTAAHCEA
RIYYVYVGLH KFINDQTPKG ITARRAIPHE DFNKTRDNDL MLLQLSEKVN FNENVRPINL
ASRTDHLLPQ RCIVSGWGFT SEDNQNLVGE LREVNLTLAK DTSCPEPHAF SSLGEIGPSH
GNSGGPLVCE GEVAYGVVFD GKCHAPPTNI AFSLKSQTIL VGL
//
