ID Q2Y7Z9_NITMU Unreviewed; 435 AA.
AC Q2Y7Z9;
DT 20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=L-lysine 6-monooxygenase (NADPH) {ECO:0000313|EMBL:ABB75122.1};
DE EC=1.14.13.59 {ECO:0000313|EMBL:ABB75122.1};
DE SubName: Full=Lysine N6-hydroxylase/L-ornithine N5-oxygenase {ECO:0000313|EMBL:SEF97036.1};
GN OrderedLocusNames=Nmul_A1825 {ECO:0000313|EMBL:ABB75122.1};
GN ORFNames=SAMN05216403_11839 {ECO:0000313|EMBL:SEF97036.1};
OS Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=323848 {ECO:0000313|EMBL:ABB75122.1, ECO:0000313|Proteomes:UP000002718};
RN [1] {ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 / NCIMB 11849 / C 71
RC {ECO:0000313|Proteomes:UP000002718};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABB75122.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB75122.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of Chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABB75122.1, ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB75122.1}, and ATCC 25196 /
RC NCIMB 11849 / C 71 {ECO:0000313|Proteomes:UP000002718};
RX PubMed=18390676; DOI=10.1128/AEM.02722-07;
RA Norton J.M., Klotz M.G., Stein L.Y., Arp D.J., Bottomley P.J., Chain P.S.,
RA Hauser L.J., Land M.L., Larimer F.W., Shin M.W., Starkenburg S.R.;
RT "Complete genome sequence of Nitrosospira multiformis, an ammonia-oxidizing
RT bacterium from the soil environment.";
RL Appl. Environ. Microbiol. 74:3559-3572(2008).
RN [4] {ECO:0000313|EMBL:SEF97036.1, ECO:0000313|Proteomes:UP000236751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nl13 {ECO:0000313|EMBL:SEF97036.1,
RC ECO:0000313|Proteomes:UP000236751};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
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DR EMBL; CP000103; ABB75122.1; -; Genomic_DNA.
DR EMBL; FNVK01000018; SEF97036.1; -; Genomic_DNA.
DR RefSeq; WP_011381142.1; NZ_FNVK01000018.1.
DR AlphaFoldDB; Q2Y7Z9; -.
DR STRING; 323848.Nmul_A1825; -.
DR KEGG; nmu:Nmul_A1825; -.
DR eggNOG; COG3486; Bacteria.
DR HOGENOM; CLU_020931_2_0_4; -.
DR OrthoDB; 7527071at2; -.
DR Proteomes; UP000002718; Chromosome.
DR Proteomes; UP000236751; Unassembled WGS sequence.
DR GO; GO:0047091; F:L-lysine 6-monooxygenase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR025700; Lys/Orn_oxygenase.
DR PANTHER; PTHR42802:SF1; L-ORNITHINE N(5)-MONOOXYGENASE; 1.
DR PANTHER; PTHR42802; MONOOXYGENASE; 1.
DR Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ABB75122.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002718}.
SQ SEQUENCE 435 AA; 49481 MW; D99B958D9C981EF7 CRC64;
MQIHDLIGIG FGPSNIALAI TLEEKKQEGY DVDAFFIEKQ PGFAWHPNMM LDNAHMQISF
LKDLATLRNP SSYFTFINYL HQKQRLQDFI NLKTFFPSRH EFNDYLAWAA SHFDDRCAYG
EEVLEVLAEK RNDEVMLLRV RSLDSTGTAR ERLARNLIVS VGGVPSVPEC FQPLKGDKRI
FHSNSYLREI ERHKEAKKIA VVGAGQSASE IFMDLHNRPN APQVDLIMRG RAIKPSDDSP
FVNEIFNTDF TDFVFSRSEH DRVSLLEEFW HTNYAAPDLV LIEQIFNVFY QQRVTGNTRH
RFLRRHEVTS VSALPEGGIQ LLLRDLNGGR EYSAIYDAVV LATGYGRDYH KSLLKSLSPY
LSNFSVDRNY RLKSTPNFRP AIFLQGACES THGLSDTLLS VTAVRTHEIG QALVGMINDP
VAKQAENPVR AVAVR
//
