ID   Q2YM24_BRUA2            Unreviewed;       558 AA.
AC   Q2YM24;
DT   07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   07-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Na+/Pi-cotransporter {ECO:0000313|EMBL:CAJ11456.1};
GN   OrderedLocusNames=BAB1_1500 {ECO:0000313|EMBL:CAJ11456.1};
OS   Brucella abortus (strain 2308).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391 {ECO:0000313|EMBL:CAJ11456.1, ECO:0000313|Proteomes:UP000002719};
RN   [1] {ECO:0000313|EMBL:CAJ11456.1, ECO:0000313|Proteomes:UP000002719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308 {ECO:0000313|EMBL:CAJ11456.1,
RC   ECO:0000313|Proteomes:UP000002719};
RX   PubMed=16299333; DOI=10.1128/IAI.73.12.8353-8361.2005;
RG   Microbial Genomics Group;
RG   Lawrence Livermore National Laboratory;
RG   and the Genome Analysis Group;
RG   Oak Ridge National Laboratory;
RA   Chain P., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; AM040264; CAJ11456.1; -; Genomic_DNA.
DR   RefSeq; WP_002964588.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YM24; -.
DR   GeneID; 3788046; -.
DR   KEGG; bmf:BAB1_1500; -.
DR   PATRIC; fig|359391.11.peg.949; -.
DR   HOGENOM; CLU_025623_2_1_5; -.
DR   PhylomeDB; Q2YM24; -.
DR   Proteomes; UP000002719; Chromosome I.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR   GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR   InterPro; IPR003841; Na/Pi_transpt.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   NCBIfam; NF037997; Na_Pi_symport; 1.
DR   PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR   Pfam; PF02690; Na_Pi_cotrans; 2.
DR   Pfam; PF01895; PhoU; 2.
DR   SUPFAM; SSF109755; PhoU-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002719};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        44..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          352..429
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
FT   DOMAIN          455..537
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
SQ   SEQUENCE   558 AA;  61313 MW;  594A80D35209A6F2 CRC64;
     MNGSLALLHL AGAVALLLWA TRMVRTGVER AYGDRLRRRL RNQMQNPLLS VAFGLALSIA
     LQSSTAVTLL VGSFVGSGFV SGVAGLMAVR GGELGSALVV KILSYDLTLL VPLCLVVGTG
     IFMTTERRDW RQIGRILVGI GLLIMSLEMT GQATEPLRRS ELLPVIVDYL SSDPVTAYLL
     AALMTWLFHS SVAAVILLTT FASRGLIHPE LAVVMVLGVN LGSSIIAPIL TRHAPPETRV
     VPLGNLLMRG AGSLIMLVLY QTFKPSVGFL GSDPVSQVVN AHILFNVLVM IAGIPLSGLV
     LRATEALVHL NADKDAPAKP MAVEEYSALD NAVLDRPSQA LANATREVVG VCDTIEVMLR
     RIIELYEKPD QARINELEAL DDRVDKKHVA IKLYLTRLAT QNLTDFESLR MQELLGACVK
     LEQVGDIIVR NMLAQVQKKM NHKLEFTEEG WKELSHFHAM VLANAHMAFN VIVSRDGRTA
     RQLVQEKDRL REMEKQTSMR HFSRLREGST RSIETSSIHL DTIRDLKQIN SLLASMAYPV
     LEEQGLLSDT RLKTAKQS
//