ID Q30E07_MICAR Unreviewed; 82 AA.
AC Q30E07;
DT 06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 06-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=MHC class II antigen {ECO:0000313|EMBL:ABA26558.1};
DE Flags: Fragment;
GN Name=Miar-DQA {ECO:0000313|EMBL:ABA26558.1};
OS Microtus arvalis (Common vole) (Field vole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Arvicolinae; Microtus.
OX NCBI_TaxID=47230 {ECO:0000313|EMBL:ABA26558.1};
RN [1] {ECO:0000313|EMBL:ABA26558.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16467985; DOI=10.1007/s00251-006-0085-6;
RA Bryja J., Galan M., Charbonnel N., Cosson J.F.;
RT "Duplication, balancing selection and trans-species evolution explain the
RT high levels of polymorphism of the DQA MHC class II gene in voles
RT (Arvicolinae).";
RL Immunogenetics 58:191-202(2006).
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DR EMBL; DQ137816; ABA26558.1; -; Genomic_DNA.
DR AlphaFoldDB; Q30E07; -.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:1903037; P:regulation of leukocyte cell-cell adhesion; IEA:UniProt.
DR GO; GO:0050863; P:regulation of T cell activation; IEA:UniProt.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR001003; MHC_II_a_N.
DR PANTHER; PTHR19944:SF59; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF00993; MHC_II_alpha; 1.
DR SMART; SM00920; MHC_II_alpha; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}.
FT DOMAIN 2..82
FT /note="MHC class II alpha chain N-terminal"
FT /evidence="ECO:0000259|SMART:SM00920"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABA26558.1"
FT NON_TER 82
FT /evidence="ECO:0000313|EMBL:ABA26558.1"
SQ SEQUENCE 82 AA; 9035 MW; B5B2A759B7995A8B CRC64;
DHVGTFGTVV YQSYGPNGQV TCEFDGDELL YVDLDKKETV WRIPEFGKLA SLDPQGGLQQ
IATAKFNLDV LTKRSNSTPV TN
//
