ID   Q30K13_VIBCL            Unreviewed;       280 AA.
AC   Q30K13;
DT   06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT   06-DEC-2005, sequence version 1.
DT   13-SEP-2023, entry version 76.
DE   SubName: Full=LytB {ECO:0000313|EMBL:AAY87627.1};
DE   Flags: Fragment;
GN   Name=lytB {ECO:0000313|EMBL:AAY87627.1};
OS   Vibrio cholerae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=666 {ECO:0000313|EMBL:AAY87627.1};
RN   [1] {ECO:0000313|EMBL:AAY87627.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=141-94 {ECO:0000313|EMBL:AAY87625.1}, and 928-93
RC   {ECO:0000313|EMBL:AAY87627.1};
RX   PubMed=16318732;
RA   Salim A., Lan R., Reeves P.R.;
RT   "Vibrio cholerae pathogenic clones.";
RL   Emerg. Infect. Dis. 11:1758-1760(2005).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; DQ021132; AAY87625.1; -; Genomic_DNA.
DR   EMBL; DQ021134; AAY87627.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q30K13; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051745; F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:InterPro.
DR   CDD; cd13944; lytB_ispH; 1.
DR   Gene3D; 3.40.50.11270; -; 1.
DR   Gene3D; 3.40.1010.20; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain; 2.
DR   HAMAP; MF_00191; IspH; 1.
DR   InterPro; IPR003451; LytB/IspH.
DR   NCBIfam; TIGR00216; ispH_lytB; 1.
DR   PANTHER; PTHR30426; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR30426:SF0; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF02401; LYTB; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAY87627.1"
FT   NON_TER         280
FT                   /evidence="ECO:0000313|EMBL:AAY87627.1"
SQ   SEQUENCE   280 AA;  30997 MW;  CC5B5D05CE77C20F CRC64;
     RGFCAGVDRA ISIVERALEL YQPPIYVRHE VVHNRFVVEG LKQRGARFVE ELNEVPDDNI
     VIFSAHGVSQ AVRQEAKERS LTVFDATCPL VTKVHMEVAR ASRKHMEVVL IGHAGHPEVE
     GTMGQYASDT GGMYLVEKPE DVVSLQAKVK DPSNLHYVSQ TTLSVDETAD VIDELRRVFP
     KIQGPRKDDI CYATQNRQDA VRILAEQVDV MVVVGSKNSS NSTRLKELAE KLGTPGYLID
     CPQDIDPEWF VAAQLIGVTA GASAPEELVN QILERIKELG
//