ID Q32NL8_XENLA Unreviewed; 693 AA.
AC Q32NL8;
DT 06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 06-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=MGC131051 protein {ECO:0000313|EMBL:AAI08569.1};
DE SubName: Full=Solute carrier family 3 (Amino acid transporter heavy chain), member 1 L homeolog {ECO:0000313|RefSeq:NP_001089867.1};
GN Name=slc3a1.L {ECO:0000313|RefSeq:NP_001089867.1,
GN ECO:0000313|Xenbase:XB-GENE-999165};
GN Synonyms=csnu1 {ECO:0000313|RefSeq:NP_001089867.1}, d2h
GN {ECO:0000313|RefSeq:NP_001089867.1}, MGC131051
GN {ECO:0000313|EMBL:AAI08569.1}, rbat
GN {ECO:0000313|RefSeq:NP_001089867.1}, slc3a1
GN {ECO:0000313|RefSeq:NP_001089867.1,
GN ECO:0000313|Xenbase:XB-GENE-999165};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAI08569.1};
RN [1] {ECO:0000313|RefSeq:NP_001089867.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI08569.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAI08569.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001089867.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC108568; AAI08569.1; -; mRNA.
DR RefSeq; NP_001089867.1; NM_001096398.1.
DR CAZy; GH13; Glycoside Hydrolase Family 13.
DR DNASU; 734933; -.
DR GeneID; 734933; -.
DR KEGG; xla:734933; -.
DR AGR; Xenbase:XB-GENE-999165; -.
DR CTD; 734933; -.
DR Xenbase; XB-GENE-999165; slc3a1.L.
DR OrthoDB; 3680211at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 734933; Expressed in intestine and 11 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11359; AmyAc_SLC3A1; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045857; O16G_dom_2.
DR InterPro; IPR031984; SLC3A2_N.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF16028; SLC3A2_N; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..567
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 79685 MW; 6CBD75C2A4F65EB6 CRC64;
MEEEPNSVEL KQKAGHENNG FISDHDGRDE DKPEKGKSRR NSKEGDAHIY SVRINEVPED
SPPLKPYAGM PKDVLLQFSN RPCYRIAREI IFWLIIVATL AIIAATIAII AISPKCLDWW
QRSPMYQVYP KSFKDSNNDG SGDLKGVQEK IDHFLYLNIK NVWVAPFYKS SLKDFNYAVD
DFMEVDPTFG TMADFESMIS AMHDKGLKLI IDLIPNHTSN KHKWFQLSRN RTGKYADYYI
WHDCMQTGGL VVPPNNWVSF YGNSAWEYDD TRKQCYLHQF KKEQPDLDFN NPDVNEEILN
IIKFWLEKGV DGFTINSAKF LLEAEHLRDE PQVNKLQNPD TISNYSELFH DYTTTQVGMH
DIIRNFRQTI NKYSREPGRY RFMGTESNDQ AAVDKTMLYY GNSFIQEADF PLNAYLFDLN
KANIDGASIF SMVDLWMKAM PSGKWPNWMV GGPSSSRIAS RVGRQYVNVM NMLLLTLPGT
PTTYYGEELG MEDGSPQVST ENPQEYNPTE YPEKTPMQWD SSSNAGFSEA NRTWLSVNPD
YEAVNVEAQK NEQYSTLNLY RELNHLRNNE LPLHRGWLCY TWSDNNVFAY VRELDGLNKV
FMMVLNFGQA WTINLRQAVP DLPGEAKIRL STEGSRVGKA VSTDSIQTQP GEGLILEYKT
NKPVHVRDTF KDKCFISEKA CYTSAFDLLY NSC
//
