ID Q33AB0_ORYSJ Unreviewed; 1849 AA.
AC Q33AB0;
DT 06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 06-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN OrderedLocusNames=LOC_Os10g12770 {ECO:0000313|EMBL:ABB47016.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000313|EMBL:ABB47016.1};
RN [1] {ECO:0000313|EMBL:ABB47016.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12791992; DOI=10.1126/science.1083523;
RG Rice Chromosome 10 Sequencing Consortium;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2] {ECO:0000313|EMBL:ABB47016.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell C.R., Wing R.A., McCombie W.R., Messing J., Yuan Q., Ouyang S.;
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABB47016.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell R.;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP000086; ABB47016.1; -; Genomic_DNA.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR45835:SF87; RNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR45835; YALI0A06105P; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 686..701
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 936..1115
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1476..1643
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 342..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 243..270
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 345..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..385
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1849 AA; 209959 MW; A92EA5D950A21B86 CRC64;
MEMDEVGGRW TFSRANEGYT SCGPVVEMSW HRAGVLLLGA QSCLPVPEVP AVGGIGSVLS
SMARMGWKLC HVFRLYTVVM AGSVTRRGLN MTGFVLELRG MCVVLGYPHG VDYQARPLPE
QEGDDAEPHA GWEVTAVILS GSPERTSLAV TAGGDSFPAA CQNAALLAIG TLHQRYPDEL
QHSPYRYHPR RGGARDYATF RDASSEDDAT IVHLARMVEA YDAARIDFHQ MVRRGMVENN
MKILELRQEN LQLKKDLDAV EAQLHQLKIA QGEVYRPKRR RVCRSQKITA RKSTSRPELV
RQSLAWTCFV ETPRAEPAPV VPQEGEASGV GSTEDALLLT FRPGPSQRRN ANTGDGNQPE
GSNHNHQGNP PPPPPPPPPP PPDTNAILTQ ILAQQANMMT AFLHHLQNPP QQNAPPPPPQ
HSKLAEFLRI RPPTFSSSNN PVDALDWLHA VGKKLDTVQY SDEEKVIFAA HQLQGPASLW
WDHFQATQPE GQPITWARFT AAFRRTHVPA GVVALKKREF RELKQGNRSV MEYLHEFNNL
ARYAPEDVRE DEEKQEKFLA GMDPELSVRL VSGDYPDFQR LVDKSIRLEA KHKELESHKR
RLANFRNQQG ANQRVRYTNP YPGGSSLQQQ QQQQQPRSAP RPQFVVRVPQ PQQQQGQQGT
RAPRPPTPTV QPGQGRRDAQ GQQRLCFNCF EPGHFADKCP KPRRQQGQAP PRSNNGGKDV
IWGRVNHVTA EDLLTTPDVI VGTFLVHSIP ATILFDSGAS HSFISVPFVG RNQLGVERLR
NPLLITTPGG VMTAKYYSPA VPIEIQGIPF PSDLILLDTK NLDVILGMNW LAQFQGVVDC
ARRTVTLYRG PEQPVVFFAP PTSVRSSELH QIGLSEIPIV REFGDVFPEE LPGMPPKREI
EFRIDLAPGT TPLHKRPYRM AANELAEVKK QLEELKEKGY IRPSTSPWGA PVIFVEKKDK
TKRMCVDYRA LNEVTIKNKY PLPRIDDLFD QLKGATVFSK IDLRSGYHQL RIREEDIPKT
AFTTRYGLYE FTVMSFGLTN APAFFMNLMN KVFMEYLDKF VVVFIDDILI YSQSEEDHQH
HLRLLLGKLR EHQLYAKLSK CEFWLSKVKF LGHVISAKGV AVDPETVTAV TDWKQPKTVT
QVRSFLGLAG YYRRFIENFS KIARPMTQLL KKEEKFVWSP QCEKAFQTLK EKLVSSPVLI
LPDTRKDFMV YCDASRQGLG CVLMQDGHVV AYASRQLRPH EGNYPTHDLE LAAVVHALKI
WRHYLIGNRC EIYTDHKSLK YIFTQSDLNL RQRRWLELIK DYDVGIHYHP GKANVVADAL
SRKSHCNILN VRGIPPELNQ QMEALNLSIV SRGFLAALEA KPTLLDQIRE AQKNDPDMHG
LLKNMKQGKA AGFTEDEHGT LWNGKQVCVP DNRELKQLIL QEAHESPYSI HPGSTKMYLD
LKEKYWWVSM KQEIAEFVAL CDVCQRVKAE HQRPAGLLQP LQVPEWKWDE IGMDFITGLP
KTQGGYDSIW VVVDRLTKVA RFIPVKTTYG GNKLAELYFA RIVSLHGVPK KIVSDRGSQF
TSHFWKKLQE ELGTRLNFST AYHPQTDGQT ERLNQILEDM LRACVLDFGK TWDKSLPYAE
FSYNNSYQAS IQMAPYEALY GRKCRTPLLW DQVGESQVFG TDILREAEAK VRIIRDNLKV
AQSRQKSYAD NRRRDLEFAV GDFVYLRVTP LRGVHRFQTK GKLAPRYVGP FRIIARRGEV
AYQLELPASL GNVHDVFHVS QLKKCLRVPS EQADSEQIEV REDLTYVERP VKILDTMERR
TRNRVIRFCK VQWSNHAEEE ATWEREDELK AAHPDLFASS SESRGRDSV
//
