ID Q38BA3_TRYB2 Unreviewed; 302 AA.
AC Q38BA3;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Ubiquitin-like protein DSK2, putative {ECO:0000313|EMBL:EAN77917.1};
GN ORFNames=Tb10.70.2220 {ECO:0000313|EMBL:EAN77917.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN77917.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN77917.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN77917.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000208; EAN77917.1; -; Genomic_DNA.
DR RefSeq; XP_822745.1; XM_817652.1.
DR AlphaFoldDB; Q38BA3; -.
DR STRING; 185431.Q38BA3; -.
DR PaxDb; 5691-EAN77917; -.
DR GeneID; 3661931; -.
DR KEGG; tbr:Tb10.70.2220; -.
DR VEuPathDB; TriTrypDB:Tb927.10.4980; -.
DR eggNOG; KOG0010; Eukaryota.
DR InParanoid; Q38BA3; -.
DR OMA; DMGFPNE; -.
DR OrthoDB; 3177594at2759; -.
DR Proteomes; UP000008524; Chromosome 10.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; ISA:GeneDB.
DR GO; GO:0051276; P:chromosome organization; ISA:GeneDB.
DR GO; GO:0007059; P:chromosome segregation; ISA:GeneDB.
DR GO; GO:0006260; P:DNA replication; ISA:GeneDB.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd14399; UBA_PLICs; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR015496; Ubiquilin.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10677:SF3; FI07626P-RELATED; 1.
DR PANTHER; PTHR10677; UBIQUILIN; 1.
DR Pfam; PF00627; UBA; 1.
DR Pfam; PF00240; ubiquitin; 1.
DR SMART; SM00165; UBA; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT DOMAIN 1..71
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 256..302
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 70..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 32186 MW; 19E61AFBA81FEBC9 CRC64;
MSITIKLTNG DKKTVEVPDL SITVIQFKEL AENAVEIPAA EQRIVLRGKV LKDTDVLSAV
GLEHGQAVHI VRGQQPKTQA TSTSAPVPGP SNPPHVASNS YSTASNAPMN SNSESSNPYM
PLAGYMPTSL SGGVNAAGMG GSFPPFSSDA AAQLMQSPLF SQMMRDMLGN PQFMQTMMQF
AGNQSRGNDA GMQQLLSDPL MMQYVMQLAS NPEFLQEMTR MVPGGGPLSA PQTPFFGQPI
PNLTGAPQGG GLSQPQGDPR VVYQSQLQQL RDMGFPNEEA NIAALQQTQG NIHFAIERLL
NG
//
