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Database: UniProt
Entry: Q39D96
LinkDB: Q39D96
Original site: Q39D96 
ID   SUCC_BURL3              Reviewed;         388 AA.
AC   Q39D96;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   26-NOV-2014, entry version 70.
DE   RecName: Full=Succinyl-CoA ligase [ADP-forming] subunit beta {ECO:0000255|HAMAP-Rule:MF_00558};
DE            EC=6.2.1.5 {ECO:0000255|HAMAP-Rule:MF_00558};
DE   AltName: Full=Succinyl-CoA synthetase subunit beta {ECO:0000255|HAMAP-Rule:MF_00558};
DE            Short=SCS-beta {ECO:0000255|HAMAP-Rule:MF_00558};
GN   Name=sucC {ECO:0000255|HAMAP-Rule:MF_00558};
GN   OrderedLocusNames=Bcep18194_A5976;
OS   Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194
OS   / 383).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=482957;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + succinate + CoA = ADP + phosphate +
CC       succinyl-CoA. {ECO:0000255|HAMAP-Rule:MF_00558}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00558};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00558};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_00558};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       succinate from succinyl-CoA (ligase route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00558}.
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00558}.
CC   -!- SIMILARITY: Belongs to the succinate/malate CoA ligase beta
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_00558}.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain. {ECO:0000255|HAMAP-
CC       Rule:MF_00558}.
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DR   EMBL; CP000151; ABB09570.1; -; Genomic_DNA.
DR   RefSeq; WP_011353083.1; NC_007510.1.
DR   RefSeq; YP_370214.1; NC_007510.1.
DR   ProteinModelPortal; Q39D96; -.
DR   SMR; Q39D96; 1-384.
DR   STRING; 269483.Bcep18194_A5976; -.
DR   EnsemblBacteria; ABB09570; ABB09570; Bcep18194_A5976.
DR   GeneID; 3751207; -.
DR   KEGG; bur:Bcep18194_A5976; -.
DR   PATRIC; 19289468; VBIBurSp120713_4111.
DR   eggNOG; COG0045; -.
DR   HOGENOM; HOG000007059; -.
DR   KO; K01903; -.
DR   OMA; AAGRICK; -.
DR   OrthoDB; EOG644ZT0; -.
DR   BioCyc; BSP269483:GHLS-2863-MONOMER; -.
DR   UniPathway; UPA00223; UER00999.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.30.1490.20; -; 1.
DR   Gene3D; 3.30.470.20; -; 1.
DR   Gene3D; 3.40.50.261; -; 1.
DR   HAMAP; MF_00558; Succ_CoA_beta; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013650; ATP-grasp_succ-CoA_synth-type.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR005811; CoA_ligase.
DR   InterPro; IPR017866; Succ-CoA_synthase_bsu_CS.
DR   InterPro; IPR005809; Succ_CoA_synthase_bsu.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR11815; PTHR11815; 1.
DR   Pfam; PF08442; ATP-grasp_2; 1.
DR   Pfam; PF00549; Ligase_CoA; 1.
DR   PIRSF; PIRSF001554; SucCS_beta; 1.
DR   SUPFAM; SSF52210; SSF52210; 1.
DR   TIGRFAMs; TIGR01016; sucCoAbeta; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS01217; SUCCINYL_COA_LIG_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Ligase; Magnesium; Manganese;
KW   Metal-binding; Nucleotide-binding; Tricarboxylic acid cycle.
FT   CHAIN         1    388       Succinyl-CoA ligase [ADP-forming] subunit
FT                                beta.
FT                                /FTId=PRO_1000082046.
FT   DOMAIN        9    244       ATP-grasp. {ECO:0000255|HAMAP-
FT                                Rule:MF_00558}.
FT   NP_BIND      35    108       ATP. {ECO:0000255|HAMAP-Rule:MF_00558}.
FT   METAL       197    197       Magnesium or manganese.
FT                                {ECO:0000255|HAMAP-Rule:MF_00558}.
FT   METAL       199    199       Magnesium or manganese.
FT                                {ECO:0000255|HAMAP-Rule:MF_00558}.
SQ   SEQUENCE   388 AA;  41282 MW;  19FACA7BB0E3DD84 CRC64;
     MKIHEYQGKE ILRKFGVAVP RGKPAFSVDE AVKVAEELGG PVWVVKAQIH AGGRGKGGGV
     KVAKSIEQVR EYANQILGMQ LVTHQTGPEG QKVNRLMVEE GADIKQELYV SLVVDRVTQK
     IVLMGSSEGG MDIEEVAEKH PELIHKVIVE PSTGLLDAQA DDLAAKIGVP AASIPQARAI
     LQGLYKAFWE TDASLAEINP LNVSSDGKVI ALDAKFNFDS NALFRHPEIV AYRDLDEEDP
     AEIEASKFDL AYISLDGNIG CLVNGAGLAM ATMDTIKLFG GEPANFLDVG GGATTEKVTE
     AFKLMLKNPD LKAILVNIFG GIMRCDVIAE GVIAGSKAVN LNVPLVVRMK GTNEDLGKKM
     LADSGLPIIS ADSMEEAAQK VVAAAAGK
//
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