ID Q39XT2_GEOMG Unreviewed; 820 AA.
AC Q39XT2;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Sensor diguanylate cyclase/phosphodiesterase, HAMP and PAS domain-containing {ECO:0000313|EMBL:ABB30942.1};
GN OrderedLocusNames=Gmet_0700 {ECO:0000313|EMBL:ABB30942.1};
OS Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=269799 {ECO:0000313|EMBL:ABB30942.1, ECO:0000313|Proteomes:UP000007073};
RN [1] {ECO:0000313|EMBL:ABB30942.1, ECO:0000313|Proteomes:UP000007073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53774 / DSM 7210 / GS-15
RC {ECO:0000313|Proteomes:UP000007073};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT "Complete sequence of Geobacter metallireducens GS-15.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABB30942.1, ECO:0000313|Proteomes:UP000007073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53774 / DSM 7210 / GS-15
RC {ECO:0000313|Proteomes:UP000007073};
RX PubMed=19473543; DOI=10.1186/1471-2180-9-109;
RA Aklujkar M., Krushkal J., DiBartolo G., Lapidus A., Land M.L., Lovley D.R.;
RT "The genome sequence of Geobacter metallireducens: features of metabolism,
RT physiology and regulation common and dissimilar to Geobacter
RT sulfurreducens.";
RL BMC Microbiol. 9:109-109(2009).
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DR EMBL; CP000148; ABB30942.1; -; Genomic_DNA.
DR RefSeq; WP_011365712.1; NC_007517.1.
DR AlphaFoldDB; Q39XT2; -.
DR STRING; 269799.Gmet_0700; -.
DR KEGG; gme:Gmet_0700; -.
DR eggNOG; COG5000; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_7; -.
DR Proteomes; UP000007073; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..265
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 270..314
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 341..393
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 425..558
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 567..820
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 820 AA; 90857 MW; BD9F853C940AD9CF CRC64;
MRIRTTLTAG CFIFALLTAL VGYFGGRAIT KISGEFDRVA EEVFPLLRTL EDLRFAGLRI
VSSSAEHTLI VKQRGDAARR GDSIVLASSG IETLDEALAR LQSLSSSLDP EERPLVADVD
RAGRRLLETS RVHLRLVLSE APEAELRSIR ERSRGEEGAF FAAVSQAFAH KSEELDAAKA
EVRQAIRTAQ FTIAVASLVA LVLAIGGGSL VAASISRPIA LLRDGVEQVG QGLLDTRVEV
TARNEIGTLA VAFNRMTGEL QFTKNEIVTA RNFLDNVIQS MADALVILST DWTIISVNPA
LCTILGYGEN ELLGSPFGRI VAGGAEEREL LREMAERGQV PERELIYLAR DGAAIPVSVS
GAVMRSPTGE VVGIVCIAHD ISERKRSEEE IRRLAFYDPL TRLPNRSLFQ DKLAQAIRRS
RTDGDMIALL FLDLDRFKDI NDTLGHAYGD QLLLAVAARL GDNLRPTEFL ARLGGDEFVF
LVTGLRDKRS VGSLAHSILE LLNTPFEIDD KELFISTSIG IALSPGDGDD GDTLLTHADM
ALYAAKEQGR NAFSFFSEEL NREARERRHL EGSLHRAFAN DEFFLEYQPQ IELRSGRIFS
FEALVRWQHP EDGLIYPNRF IPVAEETGLI RRLGEWVLRT ACLQCRQWQQ PGLPPVRVAV
NVSGHQFNQP GFIDMVDRVL EETELDPELL ELELTESSLM AGAQESIMTL IDLKVRGIHL
AIDDFGTGYS SLSYLKHFPL DRLKIDRSFV RDIVKDLDDR AIVEAIIAMA HSLGLRVLAE
GVEHEDELEL LKERGCDEVQ GFYFAHPLLP AAVEENLKVR
//
