ID Q3BES0_9GAMM Unreviewed; 386 AA.
AC Q3BES0;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:CAJ40943.1};
OS Aeromonas encheleia.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=73010 {ECO:0000313|EMBL:CAJ40943.1};
RN [1] {ECO:0000313|EMBL:CAJ40943.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S191 {ECO:0000313|EMBL:CAJ40943.1};
RA Demarta A., Kuepfer M., Riegel P., Harf-Monteil C., Tonolla M., Peduzzi R.;
RT "Genotypic characterization of A. eucrenophila-like strains and proposal
RT for a new species: Aeromonas tecta sp. nov.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; AM116971; CAJ40943.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3BES0; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 308..386
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAJ40943.1"
FT NON_TER 386
FT /evidence="ECO:0000313|EMBL:CAJ40943.1"
SQ SEQUENCE 386 AA; 42646 MW; 49B7DFAEDF13D081 CRC64;
VSGGLHGVGV SVVNALSDKL LLTIRRNGHV YEQTYHLGEP QAPLKQIGDS SSGTGSEVRF
WPSPTIFTDT LYHYEILAKR LRELSFLNSG VSIRLEDERD GREMHFCYEG GIKAFVEYLN
QNKTPIHPKV FHFSTEQDGI GVEVAMQWND AYQEGVYCFT NNIPQRDGGT HLVGFRTALT
RTLNTYMDKE DYSKKAKSAA SGDDVREGLI AVISVKVPDP KFSSQTKDKL VSSEVKTAVE
QAMGEKLGEF LLENPSDAKI VVNKIIDAAR AREAARKARE LTRRKGALDI AGLPGKLADC
QEKDPALSEL YIVEGDSAGG SAKQGRNRKN QAILPLKGKI LNVEKARFDK MISSQEVGTL
ITALGCGIGR DEYNPDKLRY HNIIIM
//
