ID RL1_STRA1 Reviewed; 229 AA.
AC Q3K004;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 01-MAY-2013, entry version 53.
DE RecName: Full=50S ribosomal protein L1;
GN Name=rplA; OrderedLocusNames=SAK_1543;
OS Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC
OS SS700).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=205921;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27591 / A909 / CDC SS700;
RX PubMed=16172379; DOI=10.1073/pnas.0506758102;
RA Tettelin H., Masignani V., Cieslewicz M.J., Donati C., Medini D.,
RA Ward N.L., Angiuoli S.V., Crabtree J., Jones A.L., Durkin A.S.,
RA DeBoy R.T., Davidsen T.M., Mora M., Scarselli M., Margarit y Ros I.,
RA Peterson J.D., Hauser C.R., Sundaram J.P., Nelson W.C., Madupu R.,
RA Brinkac L.M., Dodson R.J., Rosovitz M.J., Sullivan S.A.,
RA Daugherty S.C., Haft D.H., Selengut J., Gwinn M.L., Zhou L., Zafar N.,
RA Khouri H., Radune D., Dimitrov G., Watkins K., O'Connor K.J.,
RA Smith S., Utterback T.R., White O., Rubens C.E., Grandi G.,
RA Madoff L.C., Kasper D.L., Telford J.L., Wessels M.R., Rappuoli R.,
RA Fraser C.M.;
RT "Genome analysis of multiple pathogenic isolates of Streptococcus
RT agalactiae: implications for the microbial 'pan-genome'.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:13950-13955(2005).
CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile
CC in the ribosome, and is involved in E site tRNA release (By
CC similarity).
CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC controls the translation of the L11 operon by binding to its mRNA
CC (By similarity).
CC -!- SUBUNIT: Part of the 50S ribosomal subunit (By similarity).
CC -!- SIMILARITY: Belongs to the ribosomal protein L1P family.
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DR EMBL; CP000114; ABA44842.1; -; Genomic_DNA.
DR RefSeq; YP_330149.1; NC_007432.1.
DR ProteinModelPortal; Q3K004; -.
DR SMR; Q3K004; 6-226.
DR STRING; 205921.SAK_1543; -.
DR EnsemblBacteria; ABA44842; ABA44842; SAK_1543.
DR GeneID; 3685198; -.
DR KEGG; sak:SAK_1543; -.
DR PATRIC; 19634389; VBIStrAga82541_1499.
DR eggNOG; COG0081; -.
DR HOGENOM; HOG000207015; -.
DR KO; K02863; -.
DR OMA; YVTSTMG; -.
DR ProtClustDB; PRK05424; -.
DR BioCyc; SAGA205921:GHD7-1551-MONOMER; -.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:HAMAP.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:HAMAP.
DR Gene3D; 3.30.190.20; -; 2.
DR Gene3D; 3.40.50.790; -; 1.
DR HAMAP; MF_01318_B; Ribosomal_L1_B; 1; -.
DR InterPro; IPR005878; Ribosom_L1_bac-type.
DR InterPro; IPR002143; Ribosomal_L1.
DR InterPro; IPR016094; Ribosomal_L1_2-a/b-sand.
DR InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR InterPro; IPR023673; Ribosomal_L1_CS.
DR InterPro; IPR023674; Ribosomal_L1_SF.
DR Pfam; PF00687; Ribosomal_L1; 1.
DR PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR SUPFAM; SSF56808; Ribosomal_L1; 1.
DR TIGRFAMs; TIGR01169; rplA_bact; 1.
DR PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE 3: Inferred from homology;
KW Complete proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding.
FT CHAIN 1 229 50S ribosomal protein L1.
FT /FTId=PRO_0000230642.
SQ SEQUENCE 229 AA; 24293 MW; 6A5473E146412D7A CRC64;
MAKKSKNLRA ALEKIDSTKA YSVEEAVALA KETNFAKFDA TVEVSYNLNI DVKKADQQIR
GAMVLPAGTG KTSRVLVFAR GAKAEEAKAA GADFVGEDDL VAKIQGGWLD FDVVIATPDM
MALVGRLGRV LGPRNLMPNP KTGTVTMDVA KAVEESKGGK ITYRADKAGN VQALIGKVSF
DDAKLVDNFK AFNDVIVKAK PATAKGTYIT NLSITTTQGV GIKVDPNSL
//
