ID Q3LBY4_9MOLU Unreviewed; 185 AA.
AC Q3LBY4;
DT 08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=tRNA-uridine 2-sulfurtransferase {ECO:0000256|ARBA:ARBA00011949};
DE EC=2.8.1.13 {ECO:0000256|ARBA:ARBA00011949};
DE Flags: Fragment;
GN Name=trmU {ECO:0000313|EMBL:CAJ17809.1};
OS Candidatus Phytoplasma solani.
OC Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC Acholeplasmataceae; Phytoplasma; 16SrXII (Stolbur group).
OX NCBI_TaxID=69896 {ECO:0000313|EMBL:CAJ17809.1};
RN [1] {ECO:0000313|EMBL:CAJ17809.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16672467; DOI=10.1128/AEM.72.5.3274-3283.2006;
RA Cimerman A., Arnaud G., Foissac X.;
RT "Stolbur phytoplasma genome survey achieved using a suppression subtractive
RT hybridization approach with high specificity.";
RL Appl. Environ. Microbiol. 72:3274-3283(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in
CC tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-
CC cysteinyl-[protein]; Xref=Rhea:RHEA:47032, Rhea:RHEA-COMP:10131,
CC Rhea:RHEA-COMP:11726, Rhea:RHEA-COMP:11727, Rhea:RHEA-COMP:11728,
CC ChEBI:CHEBI:13193, ChEBI:CHEBI:15378, ChEBI:CHEBI:17499,
CC ChEBI:CHEBI:29950, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:61963, ChEBI:CHEBI:65315, ChEBI:CHEBI:87170,
CC ChEBI:CHEBI:456215; EC=2.8.1.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001042};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ970561; CAJ17809.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3LBY4; -.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:InterPro.
DR CDD; cd01998; tRNA_Me_trans; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004506; tRNA-specific_2-thiouridylase.
DR PANTHER; PTHR11933:SF5; MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1; 1.
DR PANTHER; PTHR11933; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE; 1.
DR Pfam; PF03054; tRNA_Me_trans; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:CAJ17809.1};
KW Transferase {ECO:0000313|EMBL:CAJ17809.1}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAJ17809.1"
FT NON_TER 185
FT /evidence="ECO:0000313|EMBL:CAJ17809.1"
SQ SEQUENCE 185 AA; 21141 MW; D37BF64688375BA5 CRC64;
DRNSAVAALL LKQQGYEVEA VFMRNWDSNL NFDIKGNPTL NNDICSQELD YNDALKVSLQ
LGIKLHRIDF IEEYWKKVFL SFIDAFSNNL TPNPDILCNN EIKFKAFIDY VTDKLKPDYV
AMGHYADIVT NQDLTKALAC ALDQKKDQTY FLSQLTTSQL QNIIFPLAKL TKPEVRQIAL
DNGLV
//
