ID Q3SAL2_BOVIN Unreviewed; 348 AA.
AC Q3SAL2;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=B1 bradykinin receptor {ECO:0000256|ARBA:ARBA00021062};
DE Flags: Fragment;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAZ38708.1};
RN [1] {ECO:0000313|EMBL:AAZ38708.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Aortic endothelium {ECO:0000313|EMBL:AAZ38708.1};
RX PubMed=16497154; DOI=10.1515/BC.2006.028;
RA Morissette G., Marceau F.;
RT "Molecular identification and pharmacological profile of the bovine kinin
RT B1 receptor.";
RL Biol. Chem. 387:211-215(2006).
CC -!- FUNCTION: This is a receptor for bradykinin. Could be a factor in
CC chronic pain and inflammation. {ECO:0000256|ARBA:ARBA00025112}.
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DR EMBL; DQ099495; AAZ38708.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3SAL2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004947; F:bradykinin receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0009612; P:response to mechanical stimulus; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR001186; Brdyknn_1_rcpt.
DR InterPro; IPR000496; Brdyknn_rcpt.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR10489:SF948; B2 BRADYKININ RECEPTOR; 1.
DR PANTHER; PTHR10489; CELL ADHESION MOLECULE; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00425; BRADYKININR.
DR PRINTS; PR00993; BRADYKINNB1R.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:AAZ38708.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..311
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:AAZ38708.1"
SQ SEQUENCE 348 AA; 39508 MW; 4CF8CFC39AB48551 CRC64;
MASWALLELQ TPNQSQPLPP NTTSCDEAWE AWALLHRVLP TCVLSICLCG LLGNLFVLSV
FLVARRRLNT AEIYLANLAA SDLVFVLGLP FWAENIRNEF NWPFGALLCR LVNGIIKANL
FISVFLVVAI SQDRYCVLVH PMASRRQRRR RRAQGTCLLI WAVGALLSLP TFLLRSVKAV
PELNVSACVL RYPHDAWPFV RMVELTLLSF LLPLAAIVFF NCHILAALRG RRQISRTRCG
GPREGRTTAL ILTLVSAFLL CWAPYHFFAF LEFLFQVRAV RGCFWENFID LGLQCANFFA
FVNSCLNPVI YVFWGQLFRT KVWELYKQCI PGSLTPVASS HRTEILQL
//
