ID Q3SCM5_9FABA Unreviewed; 365 AA.
AC Q3SCM5;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=caffeate O-methyltransferase {ECO:0000256|ARBA:ARBA00039011};
DE EC=2.1.1.68 {ECO:0000256|ARBA:ARBA00039011};
GN Name=COMT {ECO:0000313|EMBL:ADQ53456.1};
OS Acacia auriculiformis x Acacia mangium.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Caesalpinioideae; mimosoid clade;
OC Acacieae; Acacia.
OX NCBI_TaxID=54177 {ECO:0000313|EMBL:AAY86361.1};
RN [1] {ECO:0000313|EMBL:AAY86361.1}
RP NUCLEOTIDE SEQUENCE.
RA Sukganah A., Wickneswari R., Choong C.Y.;
RT "Full length of Acacia mangium x Acacia auriculiformis hybrid cDNA clones
RT encoding cinnamoyl-CoA reductase (CCR) and caffeic acid O-methyltransferase
RT (COMT).";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ53456.1}
RP NUCLEOTIDE SEQUENCE.
RA Sukganah A., Choong C.Y., Wickneswari R.;
RT "Discovery of SNPs in full length genomic sequences of cinnamoyl-CoA
RT reductase (CCR) and caffeic acid O-methyltransferase (COMT) from Acacia
RT mangium and Acacia auriculiformis.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Aromatic compound metabolism; phenylpropanoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004928}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ001169; AAY86361.1; -; mRNA.
DR EMBL; HQ317735; ADQ53456.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3SCM5; -.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0009809; P:lignin biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF199; FLAVONE 3'-O-METHYLTRANSFERASE 1; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Lignin biosynthesis {ECO:0000256|ARBA:ARBA00022733};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AAY86361.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AAY86361.1}.
FT DOMAIN 34..85
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 140..345
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 269
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 365 AA; 39807 MW; 3FD1A03375EDDB8C CRC64;
MGSAGETQIT PTHVNDEEAN LFAMQLASAS VLPMILKSAL ELDLLEIIAK AGPNAQLSPS
DIASQLPTKN PDAAVMLDRM MRLLACYNVL SSSLRTLPDG KIERLYGLAP VAKYLVKNED
GVSIAPLNLM NQDKVLMESW YYLTETVLEG GIPFNKAHGM TSFEYHGKDA RFNKVFNKGM
ADHSTITMKK ILETYTGFEG LKSLVDVGGG TGAVINTIVS KYPSIKGINF DLPHVIEEAP
SFPGVEHVGG DMFVSVPKAD AVFMKWICHD WSDEHCVKFL KNCYDALPEN GKVIVAECIL
PVAPDSSLAT KGVVHIDVIM LAHNPGGKER TEKEFEALAK GAGFQGFRVC CSAFNSYIME
FLKKP
//
