ID Q3UZ11_MOUSE Unreviewed; 644 AA.
AC Q3UZ11;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 08-NOV-2023, entry version 102.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
DE Flags: Fragment;
GN Name=Kdm5a {ECO:0000313|MGI:MGI:2136980};
GN Synonyms=Jarid1a {ECO:0000313|MGI:MGI:2136980};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:BAE22050.1};
RN [1] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9;
RA Carninci P., Hayashizaki Y.;
RT "High-efficiency full-length cDNA cloning.";
RL Methods Enzymol. 303:19-44(1999).
RN [2] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=11042159; DOI=10.1101/gr.145100;
RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M.,
RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.;
RT "Normalization and subtraction of cap-trapper-selected cDNAs to prepare
RT full-length cDNA libraries for rapid discovery of new genes.";
RL Genome Res. 10:1617-1630(2000).
RN [3] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=11076861; DOI=10.1101/gr.152600;
RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P.,
RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N.,
RA Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., Yamamoto R.,
RA Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S.,
RA Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y.,
RA Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y.,
RA Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.;
RT "RIKEN integrated sequence analysis (RISA) system--384-format sequencing
RT pipeline with 384 multicapillary sequencer.";
RL Genome Res. 10:1757-1771(2000).
RN [4] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=11217851; DOI=10.1038/35055500;
RG The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium;
RT "Functional annotation of a full-length mouse cDNA collection.";
RL Nature 409:685-690(2001).
RN [5] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=12466851; DOI=10.1038/nature01266;
RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team;
RT "Analysis of the mouse transcriptome based on functional annotation of
RT 60,770 full-length cDNAs.";
RL Nature 420:563-573(2002).
RN [6] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F.,
RA Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M.,
RA Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H., Nomura K.,
RA Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T.,
RA Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RG The FANTOM Consortium;
RG Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group);
RT "The Transcriptional Landscape of the Mammalian Genome.";
RL Science 309:1559-1563(2005).
RN [8] {ECO:0000313|EMBL:BAE22050.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE22050.1};
RC TISSUE=Thymus {ECO:0000313|EMBL:BAE22050.1};
RX PubMed=16141073; DOI=10.1126/science.1112009;
RG RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium;
RT "Antisense Transcription in the Mammalian Transcriptome.";
RL Science 309:1564-1566(2005).
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DR EMBL; AK134200; BAE22050.1; -; mRNA.
DR AlphaFoldDB; Q3UZ11; -.
DR PeptideAtlas; Q3UZ11; -.
DR AGR; MGI:2136980; -.
DR MGI; MGI:2136980; Kdm5a.
DR ChiTaRS; Kdm5a; mouse.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15606; PHD2_KDM5A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047970; KDM5A_PHD2.
DR InterPro; IPR013637; Lys_sp_deMease-like_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF08429; PLU-1; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 272..329
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 438..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAE22050.1"
FT NON_TER 644
FT /evidence="ECO:0000313|EMBL:BAE22050.1"
SQ SEQUENCE 644 AA; 72837 MW; 8E8CD2414ED4FA15 CRC64;
ELPRLKQELQ QARWLDEVRL TLSDPQQVTL DVMKKLIDSG VGLAPHHAVE KAMAELQELL
TVSERWEEKA KVCLQARPRH SMANLENIVN EAKNIPAFLP NVLSLKEALQ KAREWTAKVE
AIQSGNNYAY LEQLESLSAK GRPIPVRLDA LPQVESQVAA ARAWRERTGR TFLKKNSSHT
LLQVLSPRTD IGVYGSGKNR RKKVKEIIEK EKEKDLDLEP LSDLEEGLEE SRDTAMVVAV
FKEREQKEIE AMHSLRAANL AKMTIVERIE EVKFCICRKT ASGFMLQCEL CKDWFHNSCV
PLPKSSSQKK GSSWQAKDVK FLCPLCMRSR RPRLETILSL LVSLQKLPVR LPEGEALQCL
TERAMSWQDK ARQALATDEL SSALAKLSVL SQRMVEQAAR EKTEKIISAE LQKAAANPDL
QGHLPSFQQS AFNRVVSSVS SSPHQTMDYD DEETDSDEDI RETYGYDMKD TASVKSSSSL
EPNLFCDEEI PIKSEEVVTH MWTAPSFCAE HAYSSASKSC SQGSSTPRKQ PRKSPLVPRS
LEPPVLELSP GAKAQLEELM MVGDLLEVSL DETQHIWRIL QATHPPSEDR FLHIMEDDSI
EEKPLKMKGK DSSEKKRKRK LEKVEQLFGE GKQKTKELKK IDKP
//
