ID Q3V613_ORYLA Unreviewed; 278 AA.
AC Q3V613;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 136.
DE SubName: Full=Homeobox B1b {ECO:0000313|Ensembl:ENSORLP00000015484.1};
DE SubName: Full=HoxB1b {ECO:0000313|EMBL:BAE44273.1};
GN Name=hoxB1b {ECO:0000313|EMBL:BAE44273.1};
GN Synonyms=hoxb1b {ECO:0000313|Ensembl:ENSORLP00000015484.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|EMBL:BAE44273.1};
RN [1] {ECO:0000313|EMBL:BAE53484.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hd-rR {ECO:0000313|EMBL:BAE53484.1};
RA Kurosawa G., Takamatsu N., Takahashi M., Sumitomo M., Sanaka E., Yamada K.,
RA Nishi K., Matsuda M., Asakawa S., Ishiguro H., Kurosawa Y., Shimizu N.,
RA Kohara Y., Hori H.;
RT "Organization and structure of hox gene loci in medaka fish genome and
RT comparison with those of pufferfish, zebrafish and human genomes.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAE44273.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hd-rR {ECO:0000313|EMBL:BAE44273.1};
RX PubMed=16472944; DOI=10.1016/j.gene.2005.11.015;
RA Kurosawa G., Takamatsu N., Takahashi M., Sumitomo M., Sanaka E., Yamada K.,
RA Nishii K., Matsuda M., Asakawa S., Ishiguro H., Miura K., Kurosawa Y.,
RA Shimizu N., Kohara Y., Hori H.;
RT "Organization and structure of hox gene loci in medaka genome and
RT comparison with those of pufferfish and zebrafish genomes.";
RL Gene 370:75-82(2006).
RN [3] {ECO:0000313|Ensembl:ENSORLP00000015484.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000015484.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [4] {ECO:0000313|Ensembl:ENSORLP00000015484.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000015484.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; AB207999; BAE44273.1; -; Genomic_DNA.
DR EMBL; AB232921; BAE53484.1; -; Genomic_DNA.
DR RefSeq; XP_004080698.1; XM_004080650.2.
DR STRING; 8090.ENSORLP00000015484; -.
DR Ensembl; ENSORLT00000015485.2; ENSORLP00000015484.1; ENSORLG00000012369.2.
DR GeneID; 101156205; -.
DR KEGG; ola:101156205; -.
DR CTD; 30374; -.
DR eggNOG; KOG0489; Eukaryota.
DR GeneTree; ENSGT00940000159503; -.
DR HOGENOM; CLU_058839_1_0_1; -.
DR OMA; HHQTHVN; -.
DR OrthoDB; 728401at2759; -.
DR TreeFam; TF317730; -.
DR Proteomes; UP000001038; Chromosome 19.
DR Bgee; ENSORLG00000012369; Expressed in gastrula and 9 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR046327; HXA1/B1/D1.
DR PANTHER; PTHR45946:SF5; HOMEOBOX PROTEIN HOX-B1; 1.
DR PANTHER; PTHR45946; HOMEOBOX PROTEIN ROUGH-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 185..245
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 187..246
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 251..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 31058 MW; 0D8899E14539F846 CRC64;
MNSYLDYPVC NHGGANIFSA KAGYPNLNHG YVSSNSCPTA DNYAQDGRLV AANPAPLHPP
SLHQTQLDLQ FPLPGNPMYG SPLEFGHHQY GLAPDQDRSF IHAQLSPNMA PFSGDGCGPA
AGASSHYLHP SSDQRQQEFP ENVYARVPAQ CREKDVDETS KTFDWMKVKR NPPKTAVQSE
FGVPGQINVI RTNFTTKQLT ELEKEFHFNK YLTRARRIEV AASLDLNETQ VKIWFQNRRM
KQKKREKLGY VLGNPSASVE KARSSESSPK AKEINSEH
//
