ID Q3YRQ3_EHRCJ Unreviewed; 283 AA.
AC Q3YRQ3;
DT 27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Farnesyl-diphosphate synthase {ECO:0000313|EMBL:AAZ68602.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:AAZ68602.1};
GN OrderedLocusNames=Ecaj_0567 {ECO:0000313|EMBL:AAZ68602.1};
OS Ehrlichia canis (strain Jake).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Ehrlichia.
OX NCBI_TaxID=269484 {ECO:0000313|EMBL:AAZ68602.1, ECO:0000313|Proteomes:UP000000435};
RN [1] {ECO:0000313|Proteomes:UP000000435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jake {ECO:0000313|Proteomes:UP000000435};
RX PubMed=16707693; DOI=10.1128/JB.01837-05;
RA Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., Chain P.,
RA Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., Land M.,
RA Richardson P.M., Yu X.J., Walker D.H., McBride J.W., Kyrpides N.C.;
RT "The genome of the obligately intracellular bacterium Ehrlichia canis
RT reveals themes of complex membrane structure and immune evasion
RT strategies.";
RL J. Bacteriol. 188:4015-4023(2006).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000107; AAZ68602.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3YRQ3; -.
DR STRING; 269484.Ecaj_0567; -.
DR KEGG; ecn:Ecaj_0567; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_1_5; -.
DR InParanoid; Q3YRQ3; -.
DR Proteomes; UP000000435; Chromosome.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:AAZ68602.1}.
SQ SEQUENCE 283 AA; 31496 MW; 0F17E4E3AD2047DB CRC64;
MKQRLEGILS CNISELMKHY SSLLIQKLES MLPENNQDIL LTSIRYSIFS PGKHIRPFLV
NAVAQMFDVN VDRTLPVSAA VEIIHVYSLI HDDLPGMDNE EIRRGQASSH KKFNEAVAIL
TGDALLTLAF EILSTINESP LIRCRIIKTL AHAIGYQGMI QGQILDTETI AKDINEIQNI
HVLKTAQFFS AICELGGILG NASNIQLNAL ANYGLNLGHA FQIKDDIADE DQDKSKNNIL
NIINNKDAKN YASNLIDKSI EHLTIFSHKA DILHSLAGFI RNL
//
