ID Q3Z6A6_DEHM1 Unreviewed; 500 AA.
AC Q3Z6A6;
DT 27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Reductive dehalogenase, putative {ECO:0000313|EMBL:AAW39214.1};
GN OrderedLocusNames=DET1545 {ECO:0000313|EMBL:AAW39214.1};
OS Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)
OS (Dehalococcoides ethenogenes (strain 195)).
OC Bacteria; Chloroflexota; Dehalococcoidia; Dehalococcoidales;
OC Dehalococcoidaceae; Dehalococcoides.
OX NCBI_TaxID=243164 {ECO:0000313|EMBL:AAW39214.1, ECO:0000313|Proteomes:UP000008289};
RN [1] {ECO:0000313|EMBL:AAW39214.1, ECO:0000313|Proteomes:UP000008289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2266 / KCTC 15142 / 195
RC {ECO:0000313|Proteomes:UP000008289};
RX PubMed=15637277; DOI=10.1126/science.1102226;
RA Seshadri R., Adrian L., Fouts D.E., Eisen J.A., Phillippy A.M., Methe B.A.,
RA Ward N.L., Nelson W.C., Deboy R.T., Khouri H.M., Kolonay J.F., Dodson R.J.,
RA Daugherty S.C., Brinkac L.M., Sullivan S.A., Madupu R., Nelson K.E.,
RA Kang K.H., Impraim M., Tran K., Robinson J.M., Forberger H.A., Fraser C.M.,
RA Zinder S.H., Heidelberg J.F.;
RT "Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides
RT ethenogenes.";
RL Science 307:105-108(2005).
CC -!- COFACTOR:
CC Name=corrinoid; Xref=ChEBI:CHEBI:33913;
CC Evidence={ECO:0000256|ARBA:ARBA00029374};
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DR EMBL; CP000027; AAW39214.1; -; Genomic_DNA.
DR RefSeq; WP_010937220.1; NC_002936.3.
DR AlphaFoldDB; Q3Z6A6; -.
DR STRING; 243164.DET1545; -.
DR KEGG; det:DET1545; -.
DR PATRIC; fig|243164.10.peg.1460; -.
DR eggNOG; COG1600; Bacteria.
DR HOGENOM; CLU_036586_0_1_0; -.
DR InParanoid; Q3Z6A6; -.
DR Proteomes; UP000008289; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR012832; RDH.
DR InterPro; IPR028894; RDH_dom.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR NCBIfam; TIGR02486; RDH; 1.
DR NCBIfam; TIGR01409; TAT_signal_seq; 1.
DR PANTHER; PTHR42827:SF1; IRON-SULFUR CLUSTER BINDING PROTEIN; 1.
DR PANTHER; PTHR42827; IRON-SULFUR CLUSTER-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF13486; Dehalogenase; 1.
DR Pfam; PF13484; Fer4_16; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 350..382
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT REGION 133..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 54827 MW; F073A5F6052B18BC CRC64;
MSKFHSMVSR RDFMKGLGMA GAGIGAVAAS APVFHDIDEL IASDTAVQPR PWWVKERPID
DPTIEVDFDM MERHDGRNQG QSARVRAMYY GADRVLGAAA LSAAELAERT ASNYPGYTYR
SRALAGSFKR VSPGTAPGWA ETKDPAPVKT PEERGEPKWT GTPEEASRML RAAMRAYGAS
LVGYTELTQE HRDHVIFSYE KGDSNNEKYI GTDVPVTAAR PIVFENVAKA YETTEKLVIP
NVPLWEIALS TQGSNELWRS SGTLLGGFAN SNTFYNCGNL HASTYNFLRY LGYQLIGTIG
NDARYVGSEG GAAIMAGLGE ASRQKLYTLT PEYGAPGRLY GVLTDLPLEP THPIDAGIYR
FCHSCQKCAD HCPPQVISKE KEPSWDIPLT EGKETIFSVK GTKAFYNNLP LCRQYSNETS
HGCRICWGEC TFTVNRGSLV HQIIKGTVAN VSLFNTYFYK LGEAFGYGAD AEKAETWWDL
SLPTLGQDST ITAADGGYGK
//
