ID   Q3ZPC4_9HEPC            Unreviewed;        58 AA.
AC   Q3ZPC4;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   SubName: Full=NS3 protein {ECO:0000313|EMBL:AAW32603.1};
DE   Flags: Fragment;
OS   Hepacivirus hominis.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes;
OC   Amarillovirales; Flaviviridae; Hepacivirus.
OX   NCBI_TaxID=3052230 {ECO:0000313|EMBL:AAW32603.1};
RN   [1] {ECO:0000313|EMBL:AAW32603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Fet6 {ECO:0000313|EMBL:AAW32603.1};
RX   PubMed=16114108; DOI=10.1002/eji.200526067;
RA   Guglietta S., Garbuglia A.R., Pacciani V., Scotta C., Perrone M.P.,
RA   Laurenti L., Spada E., Mele A., Capobianchi M.R., Taliani G., Folgori A.,
RA   Vitelli A., Ruggeri L., Nicosia A., Piccolella E., Del Porto P.;
RT   "Positive selection of cytotoxic T lymphocyte escape variants during acute
RT   hepatitis C virus infection.";
RL   Eur. J. Immunol. 35:2627-2637(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; AY706404; AAW32603.1; -; Genomic_RNA.
DR   MEROPS; S29.002; -.
DR   euHCVdb; AY706404; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR011492; Flavi_DEAD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07652; Flavi_DEAD; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840}.
FT   DOMAIN          11..56
FT                   /note="Non-structural protein NS3-like DEAD box helicase
FT                   flavivirus"
FT                   /evidence="ECO:0000259|Pfam:PF07652"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAW32603.1"
FT   NON_TER         58
FT                   /evidence="ECO:0000313|EMBL:AAW32603.1"
SQ   SEQUENCE   58 AA;  5723 MW;  FF5895D704B9F190 CRC64;
     FLADGGCSGG AYDVIICDEC HAQDATSVLG IGTVLDQAET AGVRLTVLAT ATPPGSIT
//