ID Q400E5_LISMN Unreviewed; 237 AA.
AC Q400E5;
DT 27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 108.
DE SubName: Full=PrfA {ECO:0000313|EMBL:ACA05492.1, ECO:0000313|EMBL:HAA9721622.1};
DE SubName: Full=Positive regulatory factor A {ECO:0000313|EMBL:CAH23221.1};
GN Name=prfA {ECO:0000313|EMBL:CAH23221.1};
GN ORFNames=GIH49_05610 {ECO:0000313|EMBL:HAA9721622.1};
OS Listeria monocytogenes.
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=1639 {ECO:0000313|EMBL:CAH23221.1};
RN [1] {ECO:0000313|EMBL:CAH23221.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SLCC2376 {ECO:0000313|EMBL:CAH23221.1};
RX PubMed=16527541; DOI=10.1016/j.ijmm.2005.10.001;
RA Chatterjee S.S., Otten S., Hain T., Lingnau A., Carl U.D., Wehland J.,
RA Domann E., Chakraborty T.;
RT "Invasiveness is a variable and heterogeneous phenotype in Listeria
RT monocytogenes serotype strains.";
RL Int. J. Med. Microbiol. 296:277-286(2006).
RN [2] {ECO:0000313|EMBL:AEN80314.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FSL J2-071 {ECO:0000313|EMBL:AEN80314.1}, and FSL J2-074
RC {ECO:0000313|EMBL:AEN80320.1};
RX PubMed=21854875; DOI=10.1016/j.meegid.2011.08.001;
RA Tsai Y.H., Maron S.B., McGann P., Nightingale K.K., Wiedmann M., Orsi R.H.;
RT "Recombination and positive selection contributed to the evolution of
RT Listeria monocytogenes lineages III and IV, two distinct and well supported
RT uncommon L. monocytogenes lineages.";
RL Infect. Genet. Evol. 11:1881-1890(2011).
RN [3] {ECO:0000313|EMBL:AEN80314.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FSL J2-071 {ECO:0000313|EMBL:AEN80314.1}, and FSL J2-074
RC {ECO:0000313|EMBL:AEN80320.1};
RA Tsai Y.-H.L., Maron S.B., McGann P., Nightingale K.K., Wiedmann M.,
RA Orsi R.H.;
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ACA05492.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 19116 {ECO:0000313|EMBL:ACA05492.1};
RX PubMed=23267677; DOI=10.1186/1471-2180-12-304;
RA Roche S.M., Grepinet O., Kerouanton A., Ragon M., Leclercq A., Temoin S.,
RA Schaeffer B., Skorski G., Mereghetti L., Le Monnier A., Velge P.;
RT "Polyphasic characterization and genetic relatedness of low-virulence and
RT virulent Listeria monocytogenes isolates.";
RL BMC Microbiol. 12:304-304(2012).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPB3501;
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [6] {ECO:0000313|EMBL:HAA9721622.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HPB3501 {ECO:0000313|EMBL:HAA9721622.1};
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:0-153(2018).
RN [7] {ECO:0000313|EMBL:HAA9721622.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HPB3501 {ECO:0000313|EMBL:HAA9721622.1};
RG NCBI Pathogen Detection Project;
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EU294568; ACA05492.1; -; Genomic_DNA.
DR EMBL; JF712525; AEN80314.1; -; Genomic_DNA.
DR EMBL; JF712526; AEN80320.1; -; Genomic_DNA.
DR EMBL; AJ812220; CAH23221.1; -; Genomic_DNA.
DR EMBL; DAAEZQ010000002; HAA9721622.1; -; Genomic_DNA.
DR RefSeq; WP_003730485.1; NZ_VTIV01000003.1.
DR AlphaFoldDB; Q400E5; -.
DR PATRIC; fig|1639.1037.peg.2751; -.
DR Proteomes; UP000844471; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.20.5.460; Single helix bin; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00042; HTH_CRP_1; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159}.
FT DOMAIN 137..212
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 237 AA; 27288 MW; 6D6B19509F1F2C5B CRC64;
MNAQAEEFKK YLETNGIKPK QFHKKELIFN QWDPQEYCIF LYDGITKLTS ISENGTIMNL
QYYKGAFVIM SGFIDTETSV GYYNLEVISE QATAYVIKIN ELKELLSKNL THFFYVFQTL
QKQVSYSLAK FNDFSINGKL GSICGQLLIL TYVYGEETPD GIKITLDNLT MQELGYSSGI
AHSSAVSRII SKLKQENVIV YKNSCFYVQN LDYLKRYAPK LDEWFYLACP ATWGKLN
//
