ID   Q460T8_ARATH            Unreviewed;       392 AA.
AC   Q460T8;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   22-FEB-2023, entry version 70.
DE   SubName: Full=Chalcone synthase family protein {ECO:0000313|EMBL:AAZ23721.1};
GN   OrderedLocusNames=At4g34850 {ECO:0000313|EMBL:AAZ23721.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:AAZ23721.1};
RN   [1] {ECO:0000313|EMBL:AAZ23721.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Chiang T.-Y., Wang W.-K.;
RT   "Diverse selective modes among orthologs/ paralogs of the chalcone synthase
RT   (Chs) gene family of Arabidopsis thaliana and its relative Arabidopsis
RT   halleri subsp. gemmifera.";
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ062380; AAZ23721.1; -; mRNA.
DR   AlphaFoldDB; Q460T8; -.
DR   ExpressionAtlas; Q460T8; baseline and differential.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF10; TYPE III POLYKETIDE SYNTHASE B; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   2: Evidence at transcript level;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          13..230
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          240..389
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        166
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   392 AA;  43054 MW;  6DC0E8E1ED3B9D4A CRC64;
     MGSIDAAVLG SEKKSNPEKA TILALGKAFP HQLVMQEYLV DGYFKTTKCD DPELKQKLTR
     LCKTTTVKTR YVVMSEEILK KYPELAIEGG STVTQRLDIC NDAVTEMAVE ASRACIKNWG
     RSISDITHVV YVSSSEARLP GGDLYLAKGL GLSPDTHRVL LYFVGCSGGV AGLRVAKDIA
     ENNPGSRVLL ATSETTIIGF KPPSVDRPYD LVGVALFGDG AGAMIIGSDP DPICEKPLFE
     LHTAIQNFLP ETEKTIDGRL TEQGINFKLS RELPQIIEDN VENFCKKLIG KAGLAHKNYN
     QMFWAVHPGG PAILNRIEKR LNLSPEKLSP SRRALMDYGN ASSNSIVYVL EYMLEESKKV
     RNMNEEENEW GLILAFGPGV TFEGIIARNL DV
//