ID Q46GI0_METBF Unreviewed; 395 AA.
AC Q46GI0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 109.
DE RecName: Full=UDP-glucose/GDP-mannose dehydrogenase C-terminal domain-containing protein {ECO:0000259|SMART:SM00984};
GN OrderedLocusNames=Mbar_A0020 {ECO:0000313|EMBL:AAZ69012.1};
OS Methanosarcina barkeri (strain Fusaro / DSM 804).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=269797 {ECO:0000313|EMBL:AAZ69012.1};
RN [1] {ECO:0000313|EMBL:AAZ69012.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Fusaro {ECO:0000313|EMBL:AAZ69012.1};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Goodwin L.A., Saunders E.H., Schmutz J.,
RA Larimer F., Land M., Anderson I., Richardson P.;
RT "Complete sequence of chromosome 1 of Methanosarcina barkeri str. fusaro.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP000099; AAZ69012.1; -; Genomic_DNA.
DR AlphaFoldDB; Q46GI0; -.
DR SMR; Q46GI0; -.
DR STRING; 269797.Mbar_A0020; -.
DR PaxDb; 269797-Mbar_A0020; -.
DR KEGG; mba:Mbar_A0020; -.
DR eggNOG; arCOG00252; Archaea.
DR HOGENOM; CLU_037409_0_0_2; -.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 2.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 236..359
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 395 AA; 44358 MW; BA9B884E843ED29A CRC64;
MAALEASMKI IGENICPDCL VLIETTVAPG TTEFVALPLL KKAFQKRGID STPLLAHSFE
RVMPGRNYVA SVRDFWRVCA GCTDEARAKV EKFLSEVINT KDYPLTIMDR PIESETAKII
ENSYRATILA FLNEWSLFSE RNGVDIIKVI NAIKMRPTHS NIIFPGPGIG GYCLPKDGGL
GYWAYKHILG FEDGDEVFKI TPTAIDINDT RALHVAELTR DALRNMGHYI AGADVLICGA
SYRQDVGDTR YSGSEIVVRK LTEMGAEMRV HDPYVDHWYE MENQDTYPAS GHSWKRFFRN
QGSLTELKIE SDFSTAIKDI EALILAVPHN EYLNFEPETI VKMAGGPIAV IDCFGILSDD
DIKRYFELGC EVKALGRGHI QQIKKEVQKR KLQQL
//
