ID Q49VR9_STAS1 Unreviewed; 505 AA.
AC Q49VR9;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=Putative periplasmic glycine betaine choline-binding protein of an ABC-type transport system {ECO:0000313|EMBL:BAE19141.1};
GN OrderedLocusNames=SSP1996 {ECO:0000313|EMBL:BAE19141.1};
OS Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS 20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=342451 {ECO:0000313|EMBL:BAE19141.1, ECO:0000313|Proteomes:UP000006371};
RN [1] {ECO:0000313|EMBL:BAE19141.1, ECO:0000313|Proteomes:UP000006371}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41
RC {ECO:0000313|Proteomes:UP000006371};
RX PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT pathogenesis of uncomplicated urinary tract infection.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; AP008934; BAE19141.1; -; Genomic_DNA.
DR RefSeq; WP_002483939.1; NZ_MTGA01000039.1.
DR AlphaFoldDB; Q49VR9; -.
DR KEGG; ssp:SSP1996; -.
DR PATRIC; fig|342451.11.peg.1990; -.
DR eggNOG; COG1174; Bacteria.
DR eggNOG; COG1732; Bacteria.
DR HOGENOM; CLU_038355_0_1_9; -.
DR OrthoDB; 9801163at2; -.
DR Proteomes; UP000006371; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015675; P:nickel cation transport; IEA:UniProtKB-KW.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13610; PBP2_ChoS; 1.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30177; GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR30177:SF4; OSMOPROTECTANT IMPORT PERMEASE PROTEIN OSMW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023112};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Nickel transport {ECO:0000256|ARBA:ARBA00023112};
KW Reference proteome {ECO:0000313|Proteomes:UP000006371};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 23..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 80..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 133..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 19..198
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 505 AA; 55726 MW; C43A739C9F79EDD7 CRC64;
MNAFIDTLIQ RRGELLTTIF EHIQISFIAL LIAALIGVPL GIALTKTRKL SEVIMNIAAV
LQTIPSLALL GLMIPLFGIG KVPAVIALVV YALLPILRNT YTGINEVDPS LVEAAKGIGM
KPGRRLSKVE LPIAMPVIMA GIRTAMVLII GTATLAALIG AGGLGDLILL GIDRNDTSLI
LIGAIPAALL AILFDLVLRY MQNMSYKKLL ISLGVIVIIL LLVIIAPMLG QKGDKVTLAG
KLGSEPSVIT NMYKILIEQD TEDTVEVKDG MGKTSFLFNA LKSDDIDGYL EFTGTVLGEL
TKEDLKSKKE AQVYQQAKSS LEDKFDMTML KPMKYNNTYA LAVKRDFAEA HHIKTIGDLN
KVSDQIKPGF TLEFNDRGDG YPAVKKAYDL DLGDVKTMEP KLRYQAIENG DINLIDAYST
DAELKEYDMV VLEDDKHVFP PYQGAPMFKE SYLKEHPEIK KPLNKLEGKI SDEDMQQMNY
DVTVKNKDPY QVAKDYLEKH NLIKH
//
