ID   Q49X77_STAS1            Unreviewed;       586 AA.
AC   Q49X77;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 107.
DE   SubName: Full=Putative pyruvate flavodoxin ferredoxin oxidoreductase alpha subunit {ECO:0000313|EMBL:BAE18621.1};
GN   OrderedLocusNames=SSP1476 {ECO:0000313|EMBL:BAE18621.1};
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS   20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=342451 {ECO:0000313|EMBL:BAE18621.1, ECO:0000313|Proteomes:UP000006371};
RN   [1] {ECO:0000313|EMBL:BAE18621.1, ECO:0000313|Proteomes:UP000006371}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41
RC   {ECO:0000313|Proteomes:UP000006371};
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA   Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
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DR   EMBL; AP008934; BAE18621.1; -; Genomic_DNA.
DR   RefSeq; WP_011303240.1; NZ_MTGA01000034.1.
DR   AlphaFoldDB; Q49X77; -.
DR   KEGG; ssp:SSP1476; -.
DR   PATRIC; fig|342451.11.peg.1479; -.
DR   eggNOG; COG0674; Bacteria.
DR   eggNOG; COG1014; Bacteria.
DR   HOGENOM; CLU_017038_1_0_9; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000006371; Chromosome.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   NCBIfam; TIGR03710; OAFO_sf; 1.
DR   PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01558; POR; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:BAE18621.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006371}.
FT   DOMAIN          14..174
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
FT   DOMAIN          210..452
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          476..550
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
FT   REGION          434..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   586 AA;  64702 MW;  90CDEEF20707CA23 CRC64;
     MKSQVSWKVG GQQGEGIEST GEIFATAMNR KGYYLYGYRH FSSRIMGGHT NNKIRVSTTP
     VHAISDDLDI LIAFDQETIE LNHHEMREDS VIIADSKAKP EKPDNCRAQL IDLPFTATAK
     ELGTALMKNM VAIGATCAVM DLDISDFETL ITNMFTKKGD KVVELNIEAL NEGYRLMNEQ
     LNNVDADFIL DKTDGKPHLY MIGNDAIGLG ALSAGSRFMA AYPITPASEI MEYMIENLPK
     VGGTVVQTED EIAAANMAIG SNYAGVRAFT ASAGPGLSLM MEAIGLSGMT ETPFVVINTQ
     RGGPSTGLPT KQEQSDLMQM IYGTHGDIPK IVVAPTDAED AFYLTMEAFN LAEQYQCPVI
     VLSDLQLSLG KQTVEQLDYN KIEINRGDMI QSDIEREEND KTYFKRYALT ESGVSPRPIP
     GVKGGIHHVT GVEHNEEGKT SEAADNRQQQ MDKRMRKTEN LLIQNPVEAD VQHETADILY
     LGFISTKGAI QEGKSRLESQ NIKVNHIQIR QLHPFPSETI QKEVDKASKV VVVEHNYQGQ
     LANILKMNVN LGDKLVNQTK YDGTPFLPHE IEANGLEIAK EIKELV
//