ID Q4D9F0_TRYCC Unreviewed; 369 AA.
AC Q4D9F0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Methyltransferase small domain-containing protein {ECO:0000259|Pfam:PF05175};
GN ORFNames=Tc00.1047053508979.80 {ECO:0000313|EMBL:EAN89155.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN89155.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN89155.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN89155.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN89155.1}.
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DR EMBL; AAHK01000779; EAN89155.1; -; Genomic_DNA.
DR RefSeq; XP_811006.1; XM_805913.1.
DR AlphaFoldDB; Q4D9F0; -.
DR PaxDb; 353153-Q4D9F0; -.
DR EnsemblProtists; EAN89155; EAN89155; Tc00.1047053508979.80.
DR GeneID; 3541904; -.
DR KEGG; tcr:508979.80; -.
DR InParanoid; Q4D9F0; -.
DR OMA; CELEWGE; -.
DR OrthoDB; 122159at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF98; PROTEIN-LYSINE N-METHYLTRANSFERASE EFM6; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 88..219
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 369 AA; 40912 MW; EB77277288CCE8DD CRC64;
MHYEDFGVIT AENGASSLSF ELACATAMDH YIRCTAPHDK QETDKYMSPC STGLRVYEGA
RVLAAFVARF GRVLLPYTFE YDTFRYPSSW VVELGCGCGL VGFTAAALFP ELSVAFTDAS
VDCLNLIGAS AERNGLTLIQ INGKGFSGVF ENNEHRVLVA YPLEWCEDDT VRLISTIRRF
SNSPNHVKTG DIRMVLGSDL LYYRVDIKTL LTTCKCLLQS SEETASKDQC NTSLAPRLAI
LAHFMRIPDG DAKLQMVAYE LGFGIVRVPL EAFVDADVIK KRGWNGISVV LLFLRSLPHT
DLHCLNIGSL CEQHEEEDLA EVKRIFSVCH ISFPSEALVC YSKKALGNNA DAFVDCEKGS
DLDNLPFFF
//
