ID Q4DGZ6_TRYCC Unreviewed; 300 AA.
AC Q4DGZ6;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=N-acetyltransferase domain-containing protein {ECO:0000259|PROSITE:PS51186};
GN ORFNames=Tc00.1047053511809.120 {ECO:0000313|EMBL:EAN91805.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN91805.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN91805.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN91805.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the acetyltransferase family. MAK3 subfamily.
CC {ECO:0000256|ARBA:ARBA00024025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN91805.1}.
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DR EMBL; AAHK01000491; EAN91805.1; -; Genomic_DNA.
DR RefSeq; XP_813656.1; XM_808563.1.
DR AlphaFoldDB; Q4DGZ6; -.
DR SMR; Q4DGZ6; -.
DR STRING; 353153.Q4DGZ6; -.
DR PaxDb; 353153-Q4DGZ6; -.
DR EnsemblProtists; EAN91805; EAN91805; Tc00.1047053511809.120.
DR GeneID; 3545071; -.
DR KEGG; tcr:511809.120; -.
DR eggNOG; KOG3139; Eukaryota.
DR InParanoid; Q4DGZ6; -.
DR OMA; EEMNFIV; -.
DR OrthoDB; 20718at2759; -.
DR BRENDA; 2.3.1.256; 6524.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR044542; NAA30-like.
DR PANTHER; PTHR45896; N-ALPHA-ACETYLTRANSFERASE 30; 1.
DR PANTHER; PTHR45896:SF1; N-ALPHA-ACETYLTRANSFERASE 30; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 118..280
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 300 AA; 33852 MW; 02882BAF8FF427BA CRC64;
MPKKTGKKGG YDVSDETLDA LVEAIEGDSN LNLQKSSKKG MTKKQALALS EKKVDDVICK
IKGTKNGMTF NEEQLRMALF AQRMMQEKAI RDAQYLNVVV PLKEDQIKWQ EVAPKRYIRY
EQFDGSQNAM EFVVGLFTKE LTEPYSSFTY EYFVFGWPDL TVIAYGIESE TFPDSSVKGE
RVGAVVSRVT RKGPGRPLRG YVAMFAVVPE FRGFRLGGRL VALTINLMRE KGCEEVYLET
PLMNERALSL YLGLGFVKTK FLPRYYLDQS DAVRLKLWLN VAITSSEEAA IGTGDVHEIS
//
