ID Q4DN84_TRYCC Unreviewed; 240 AA.
AC Q4DN84;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EAN93985.1};
DE Flags: Fragment;
GN ORFNames=Tc00.1047053511077.7 {ECO:0000313|EMBL:EAN93985.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN93985.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN93985.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN93985.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN93985.1}.
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DR EMBL; AAHK01000309; EAN93985.1; -; Genomic_DNA.
DR RefSeq; XP_815836.1; XM_810743.1.
DR AlphaFoldDB; Q4DN84; -.
DR PaxDb; 353153-Q4DN84; -.
DR EnsemblProtists; EAN93985; EAN93985; Tc00.1047053511077.7.
DR GeneID; 3547623; -.
DR KEGG; tcr:511077.7; -.
DR VEuPathDB; TriTrypDB:TcCLB.511077.7; -.
DR InParanoid; Q4DN84; -.
DR OMA; CTHFEET; -.
DR OrthoDB; 139844at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR036278; Sialidase_sf.
DR Pfam; PF13859; BNR_3; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 101..233
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 240
FT /evidence="ECO:0000313|EMBL:EAN93985.1"
SQ SEQUENCE 240 AA; 25935 MW; EC4EE1D90ABB18A7 CRC64;
MFSRVAAMKA PRTHNRRRVT GSSGRRREGR ESEPQRPNMS RHLFCSAVLL LVLVMMCCGS
GAAHAEQTGA TVDPFTGTTP ISFANWKGFN EAGRKITSLR APGLVKVGED VFAVAESQCG
EEKGAGRRAG IVSKHLNISG DPMDISTSDI SLFCMQLGDT AANNFGTTEV LRPTTLVFGN
SVYMLLGNQS HTKPQFQGEN ERGLLLVKGT VANEGGNNKK LLWNEAHVVK PEPRGDSYSL
//
