ID Q4DUL7_TRYCC Unreviewed; 514 AA.
AC Q4DUL7;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE SubName: Full=Ion transport protein, putative {ECO:0000313|EMBL:EAN96201.1};
GN ORFNames=Tc00.1047053511245.30 {ECO:0000313|EMBL:EAN96201.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN96201.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN96201.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN96201.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN96201.1}.
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DR EMBL; AAHK01000165; EAN96201.1; -; Genomic_DNA.
DR RefSeq; XP_818052.1; XM_812959.1.
DR AlphaFoldDB; Q4DUL7; -.
DR SMR; Q4DUL7; -.
DR PaxDb; 353153-Q4DUL7; -.
DR EnsemblProtists; EAN96201; EAN96201; Tc00.1047053511245.30.
DR GeneID; 3550234; -.
DR KEGG; tcr:511245.30; -.
DR eggNOG; KOG3684; Eukaryota.
DR InParanoid; Q4DUL7; -.
DR OMA; FHESSEY; -.
DR OrthoDB; 4200919at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 236..303
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 514 AA; 58940 MW; 6057590854F0B307 CRC64;
MDSASGSSRS SPRRRENRGF LRLLRRKTRA FTLGPRLLGT RVKHLLRDEL YFDVSLHSAP
SVVTNEIASL ELLAAYHRWL RGVQALLAVL VFILSLLPSA AVVEWTILAV SEAAVLIILR
VYSIKAEYTG LTNVLYRDHR NIFTSPFLLQ MLLEIIVWNI QTPPLIFFWR PFFELLDYFI
FVRLYAVAFY IHNAAYVYRF FCRAMTAMTA MPLTTSFTVR TALVYRKAKI VSLATLLSWV
TLSFMYAKAE HVPLHDGFWY AFQAISTVGY GDITPATTAG KLVAFIAWVI SFVLIAYLVV
IFHGSLTKNE NEHNMYMLMR CQRLSHLLRE DSARVIQTMW RFHRLKSPFS DGKMQCAKAL
FYSWALTRNI SRLRRERQEW RDATQRFRAS RVSPSIGFLD QGHEEHLCHL LRAAQHAQQQ
ADVDAFFRKC VECRERMPTR EEVERTVMNN FWRGSFHSTD TVGVCGATTA HVDVTNLLEK
VETLENTCSR LAALMESLAA TAPTNPPSLA HSCS
//
